name node_type short_name functional_cluster_id reaction_id reaction_type reaction_effect additional_information pathway all_pathways description evidence_sentence experimental_techniques external_links family function classification components ath_homologues nta_homologues osa_homologues stu_homologues sly_homologues LHB1B1|VPg Complex Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis,Stress - Biotic LHB1B1[AT2G34430],VPg VPg ForeignCoding Stress - Biotic Stress - Biotic viral protein genome-linked doi:10.1016/j.coviro.2012.09.004 virus LHB1B1[AT2G34430] PlantCoding LHB1B1 fc00367 Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis light-harvesting chlorophyll-protein complex II subunit B1 AT2G34430 PSB33|VPg Complex Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis,Stress - Biotic PSB33[AT1G71500],VPg PSB33[AT1G71500] PlantCoding PSB33 fc00364 Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis Rieske (2Fe-2S) domain-containing protein AT1G71500 CRT|HC-Pro Complex Signalling - Calcium Signalling - Calcium HC-Pro ForeignCoding papain-like cysteine protease with suppressor activity (multifunctional) Stress - Biotic Stress - Biotic Helper Component PROteinase doi:10.1016/j.coviro.2012.09.004 virus CRT[AT1G08450,AT1G09210,AT1G56340] PlantCoding CRT fc00048 Non-receptor component required for EFR-mediated immunity. Signalling - Calcium Signalling - Calcium calreticulin 1,2,3 gmm:30.3 CRT AT1G08450,AT1G09210,AT1G56340 OSCA1[AT4G04340] PlantCoding OSCA1 fc00389 Stress - Drought Stress - Drought AT4G04340 Drought ForeignAbiotic Stress - Drought Stress - Drought AREB/ABF[AT1G45249,AT1G49720,AT3G19290,AT4G34000] PlantCoding AREB/ABF fc00397 Hormone - Abscisic acid (ABA) Hormone - Abscisic acid (ABA) AT1G45249,AT3G19290,AT1G49720,AT4G34000 SNRK2[AT1G10940,AT1G78290,AT4G33950,SOTUB02G032470.1.1] PlantCoding SNRK2 fc00318 Hormone - Abscisic acid (ABA) Hormone - Abscisic acid (ABA) Protein kinase superfamily protein, SNF1-RELATED PROTEIN KINASE 2.8 gmm:29.4.1 AT1G10940,AT1G78290,AT4G33950 SOTUB02G032470.1.1 ARR-A[AT1G10470,AT1G19050,AT1G59940,AT1G74890,AT2G40670,AT2G41310,AT3G48100,AT3G56380,AT3G57040,AT5G62920] PlantCoding ARR-A fc00029 type-A negative response regulator Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) type-A Arabidopsis Response Regulators gmm:27.3.5 ARR AT3G56380,AT3G48100,AT1G19050,AT1G74890,AT3G57040,AT5G62920,AT1G10470,AT2G41310,AT2G40670,AT1G59940 EDF2|HC-Pro Complex Hormone - Ethylene (ET) Hormone - Ethylene (ET) EDF2[AT1G68840] PlantCoding EDF2 fc00059 Rav2 is part of a complex that has been named 'regulator of the (H+)-ATPase of the vacuolar and endosomal membranes' (RAVE) Hormone - Ethylene (ET) Hormone - Ethylene (ET) related to ABI3/VP1 2 kegg:k09287,gmm:27.3.3 ERF/EDF AT1G68840 CML|HC-Pro Complex Signalling - Calcium Signalling - Calcium CML[AT1G66410,AT3G01830,AT4G20780,SOTUB02G034770.1.1] PlantCoding CML fc00224 Calcium-binding EF-hand family protein. Includes putative, calmodulin and calmodulin like. Signalling - Calcium Signalling - Calcium calmodulin related gmm:30.3 CAM AT1G66410,AT3G01830,AT4G20780 SOTUB02G034770.1.1 CA-CoA Metabolite Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) Cinnamoyl-CoA chebi:15463,pubchem:195898,metacyc:cinnamoyl-coa,c00540,c00540 CA Metabolite Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) Cinnamate chebi:23252,metacyc:CPD-674 BZO1[AT1G65880] PlantCoding BZO1 fc00323 Secondary metabolism - Terpenoids Secondary metabolism - Terpenoids benzoyloxyglucosinolate 1 AT1G65880 EDS1|PAD4 Complex Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) PAD4[AT3G52430] PlantCoding PAD4 fc00123 Encodes a lipase-like gene that is important for salicylic acid signaling and function in resistance (R) gene-mediated and basal plant disease resistance. Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) phytoalexin deficient, InterPro Lipase, class 3 gmm:20.1.7.1,mm:26.9.2.4.2 PAD4 AT3G52430 EDS1[AT3G48090] PlantCoding EDS1 fc00060 Component of R gene-mediated disease resistance in Arabidopsis thaliana with homology to eukaryotic lipases. Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) enhanced disease susceptibility, alpha/beta-Hydrolases superfamily protein gmm:20.1.7.1 EDS1 AT3G48090 EDS1|MPK3|PAD4 Complex Signalling - MAP kinases (MAPKs) Signalling - MAP kinases (MAPKs) MPK3,6[AT2G43790,AT3G45640] PlantCoding MPK3,6 fc00308 Encodes a MAP kinase induced by pathogens, ethylene biosynthesis, oxidative stress and osmotic stress. Signalling - MAP kinases (MAPKs) Signalling - MAP kinases (MAPKs) mitogen-activated protein (MAP) kinase 3,6 gmm:29.4,gmm:30.6 MAPK AT2G43790,AT3G45640 SERPIN1|VPg Complex Signalling - Cell death Signalling - Cell death,Stress - Biotic SERPIN1[AT1G47710],VPg SERPIN1[AT1G47710] PlantCoding SERPIN1 fc00362 Signalling - Cell death Signalling - Cell death Serine protease inhibitor (SERPIN) family protein AT1G47710 CLPP1|VPg Complex clpP1[ATCG00670],VPg clpP1[ATCG00670] PlantCoding clpP1 fc00363 plastid-encoded CLP P ATCG00670 FQR1|VPg Complex Hormone - Auxins (AUX) Hormone - Auxins (AUX),Stress - Biotic FQR1[AT5G54500],VPg FQR1[AT5G54500] PlantCoding FQR1 fc00366 Hormone - Auxins (AUX) Hormone - Auxins (AUX),Signalling - Reactive oxygen species (ROS) flavodoxin-like quinone reductase 1 AT5G54500 PR-3|VPg Complex [ORF]F18O19.30[AT2G43590],VPg PR-3 like[AT2G43590] PlantCoding PR-3 like fc00361 Stress - Biotic Stress - Biotic Chitinase family protein AT2G43590 HC-Pro|TDX Complex Signalling - Reactive oxygen species (ROS) Signalling - Reactive oxygen species (ROS) TDX[AT3G17880] PlantCoding TDX fc00153 Tetraticopeptide domain-containing thioredoxin; Encodes a thioredoxin-like disulfide reductase. The protein interacts with the yeast Hsp70 protein Ssb2 in vitro. This interaction is sensitive to the redox status of the thioredoxin domain of AtTDX. Signalling - Reactive oxygen species (ROS) Signalling - Reactive oxygen species (ROS) tetracopeptide domain-containing thioredoxin gmm:21.1 TDX AT3G17880 P3|RBC Complex Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis P3 ForeignCoding Stress - Biotic Stress - Biotic cell-to-cell movement doi:10.1016/j.coviro.2012.09.004 virus RBC[AT1G67090,AT5G38430,ATCG00490] PlantCoding RBC fc00314 Encodes a member of the Rubisco small subunit (RBCS) multigene family: RBCS1A (AT1G67090), RBCS1B (AT5G38430), RBCS2B (AT5G38420), and RBCS3B (AT5G38410). Large subunit of RUBISCO (ATCG00490) protein is tyrosine-phosphorylated and its phosphorylation state is modulated in response to ABA in Arabidopsis thaliana seeds. When phosphorylated it is modulated in response to ABA. Functions to yield sufficient Rubisco content for leaf photosynthetic capacity. RuBisCO catalyzes two reactions- the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis ribulose-bisphosphate carboxylase gmm:1.3 RBCL AT1G67090,AT5G38430,ATCG00490 NAC055[AT3G15500] PlantCoding NAC055 fc00111 Regulation - Transcription & Translation Regulation - Transcription & Translation ATAF-like NAC-domain transcription factor gmm:27.3.27,tair:locus:2090176 NAC AT3G15500 OBE1|VPg Complex Signalling - Perception and resistance genes Signalling - Perception and resistance genes OBE1[AT3G07780] PlantCoding OBE1 fc00116 Together with OBE2, required for the maintenance and/or establishment of both the shoot and root meristems, probably by controlling the expression of the meristem genes such as WUS, PLT1 and PLT2 and of genes required for auxin responses. Promotes cell meristematic activity via the WUSCHEL-CLAVATA pathway. Involved in the development of the basal pole and in auxin-mediated root and vascular development in the embryo. Confers sensitivity to turnip mosaic virus (TuMV) probably by promoting viral movement and multiplication via interaction with TuMV VPg. Signalling - Perception and resistance genes Signalling - Perception and resistance genes oberon 1 gmm:31.1 OBE AT3G07780 RH8|VPg Complex Regulation - Silencing Regulation - Silencing RH8[AT4G00660] PlantCoding RH8 fc00140 Putative; involved in viral reproduction, viral-host interaction; ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping. Regulation - Silencing Regulation - Silencing RNAhelicase-like 8 (DEAD/DEAH box helicase) gmm:28.1 RH AT4G00660 RPS12C|VPg Complex Regulation - Transcription & Translation Regulation - Transcription & Translation,Stress - Biotic RPS12C[AT2G32060],VPg RPS12C[AT2G32060] PlantCoding RPS12C fc00369 Regulation - Transcription & Translation Regulation - Transcription & Translation Ribosomal protein L7Ae/L30e/S12e/Gadd45 family protein AT2G32060 MTI20.11|VPg Complex Degradation - Ubiquitination Degradation - Ubiquitination,Stress - Biotic MTI20.11[AT5G57860],VPg MTI20.11[AT5G57860] PlantCoding MTI20.11 fc00370 Degradation - Ubiquitination Degradation - Ubiquitination Ubiquitin-like superfamily protein AT5G57860 CRT|Ca2+ Complex Signalling - Calcium Signalling - Calcium Ca2+ Metabolite Signalling - Calcium Signalling - Calcium Calcium chebi:22984 SAMS[AT1G02500,AT2G36880,AT3G17390,AT4G01850] PlantCoding SAMS fc00146 Hormone - Ethylene (ET) Hormone - Ethylene (ET) S-adenosylmethionine (SAM) synthetase gmm:13.1.3.4.11,ec:2.5.1.6 SAM AT1G02500,AT2G36880,AT3G17390,AT4G01850 SAHH[AT3G23810] PlantCoding SAHH fc00144 Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) S-adenosyl-l-homocysteine (SAH) hydrolase 2 gmm:13.2.3.4 SAHH AT3G23810 HSP90|RAR1|SGT1 Complex Signalling - Heat-shock proteins (HSPs) Signalling - Heat-shock proteins (HSPs) RAR1[AT5G51700] PlantCoding RAR1 fc00135 Required for R protein accumulation. Functions as positive regulator of RPS5 accumulation by assisting its stabilization. May function as co-chaperone of HSP90-2 to positively regulate the steady-state accumulation of RPM1 and protect it from SGT1- mediated degradation. Signalling - Perception and resistance genes Signalling - Perception and resistance genes resistance signalling protein, cysteine and histidine-rich domain-containing protein gmm:20.1.7 RAR1 AT5G51700 HSP90[AT2G04030,AT3G07770,AT4G24190,AT5G52640,AT5G56000,AT5G56010,AT5G56030] PlantCoding HSP90 fc00083 Signalling - Heat-shock proteins (HSPs) Signalling - Heat-shock proteins (HSPs) heat shock protein 90 gmm:20.2.1,metacyc:eg10461,kegg:k09487 HSP AT5G56010,AT5G52640,AT4G24190,AT3G07770,AT5G56000,AT2G04030,AT5G56030 SGT1[AT4G11260,AT4G23570] PlantCoding SGT1 fc00149 two functionally redundant proteins in resistance to pathogens; SGT1/RAR1/HSP90/R protein complex mediates downstream MAP kinase activation and changes in defense gene expression and hormone levels; Functions in plant disease resistance signaling, SCF(TIR1) mediated degradation of Aux/IAA proteins and HSP90 mediated degradation of R resistance proteins Signalling - Perception and resistance genes Signalling - Perception and resistance genes SGT1 protein binding; suppressor of the g2 allelle of SKP1 gmm:29.4,pubchem:160729492,kegg:k12795 SGT1 AT4G11260,AT4G23570 PR5|VPg Complex PR5[AT1G75040],VPg PR5[AT1G75040] PlantCoding PR5 fc00132 Thaumatin-like protein involved in response to pathogens. Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) pathogenesis-related protein 5; thaumatin-like protein gmm:20.1.7.5 PR5 AT1G75040 AGO1,5,7,10|HC-Pro Complex Regulation - Silencing Regulation - Silencing AGO1[AT1G48410] PlantCoding AGO1 fc00017 Regulation - Silencing Regulation - Silencing argonaute, stabilizer of iron transporter SufD / Polynucleotidyl transferase gmm:27.3.36 AGO AT1G48410 EDS1|PAD4|SAG Complex Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) SAGs[AT5G14930,AT5G45890] PlantCoding SAGs fc00317 acyl hydrolase involved in senescence; EDS1/PAD4/SAG101 complex regulates HRT-mediated resistance against TCV. Cysteine protease, CK/AUX and sugar influenced. Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) Senescence Associated Genes gmm:33.99,gmm:29.5.3 SAG101 AT5G14930,AT5G45890 AGO1,5,7,10|CI Complex Regulation - Silencing Regulation - Silencing CI ForeignCoding Stress - Biotic Stress - Biotic RNA helicase with ATPase activity doi:10.1016/j.coviro.2012.09.004 virus CP|CPIP Complex Signalling - Heat-shock proteins (HSPs) Signalling - Heat-shock proteins (HSPs) CPIP[AT1G10350,AT3G08910] PlantCoding CPIP fc00300 Putative in Arabidopsis. Capsid protein interacting proteins (CPIP) in Nicotiana tabacum (closest match to ntaCPIP1, ntaCPIP2a, ntaCPIP2b). Signalling - Heat-shock proteins (HSPs) Signalling - Heat-shock proteins (HSPs) DNAJ heat shock family protein gmm:20.2.1 HSP AT1G10350,AT3G08910 nta.4050 CP ForeignCoding Stress - Biotic Stress - Biotic capsid/coat protein doi:10.1016/j.coviro.2012.09.004 virus ATG13A[AT3G49590] PlantCoding ATG13A fc00330 Degradation - Autophagy Degradation - Autophagy Protein kinase superfamily protein pmid:21984698,doi:10.1105/tpc.111.090993 AT3G49590 TORC1 Complex Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis doi:10.1242/dev.160887,doi:10.1093/jxb/eraa603 TOR[AT1G50030],RAPTOR2[AT5G01770] DXPS2|HC-Pro Complex Secondary metabolism - Terpenoids Secondary metabolism - Terpenoids DXPS2[AT4G15560] PlantCoding DXPS2 fc00057 Secondary metabolism - Terpenoids Secondary metabolism - Terpenoids 1-deoxy-D-xylulose-5-phosphate synthase ec:2.2.1.7,kegg:ec00900,gmm:16.1.1.1 DXPS AT4G15560 ATPB|HC-Pro Complex Secondary metabolism - Terpenoids Secondary metabolism - Terpenoids ATPB[ATCG00480] PlantCoding ATPB fc00032 chloroplastic Secondary metabolism - Terpenoids Secondary metabolism - Terpenoids ATP synthase subunit beta gmm:1.1.4.2,gmm:9.9 ATPB ATCG00480 NDR1|RIN4 Complex Signalling - Perception and resistance genes Signalling - Perception and resistance genes NDR1[AT3G20600] PlantCoding NDR1 fc00113 Downstream of CC-NBS-LRR-mediated resistance; Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family. Mediates SAR; resistance against bacterial and fungal pathogens. Involved in disease resistance. Required for resistance conferred by multiple R genes recognizing different bacterial and oomycete pathogen isolates like avirulent P.syringae or H.parasitica (downy mildew). Required for the establishment of hypersensitive response (HR) and systemic acquired resistance (SAR) after infection with the bacterial pathogen P.syringae DC3000 carrying avrRpt2. Required for resistance to the soilborne fungus V.longisporum. Interaction with RIN4 is required for the activation of the R gene RPS2 and RPS2-mediated resistance. The mRNA is cell-to-cell mobile. Signalling - Perception and resistance genes Signalling - Perception and resistance genes non race-specific disease resistance 1 gmm:20.1.2 NDR AT3G20600 RIN4[AT3G25070] PlantCoding RIN4 fc00141 Member of the R protein complex. Essential regulator of plant defense, which plays a central role in resistance in case of infection by a pathogen. It is a common target for both type III avirulence proteins from P.syringae (AvrB, AvrRpm1 and AvrRpt2) and for the plant Resistance (R) proteins RPM1 and RPS2. Signalling - Perception and resistance genes Signalling - Perception and resistance genes RPM1 interacting protein 4 gmm:20.1 RIN4 AT3G25070 HC-Pro|MIND1 Complex Secondary metabolism - Terpenoids Secondary metabolism - Terpenoids MIND1[AT5G24020] PlantCoding MIND1 fc00103 chloroplastic; septum site-determining protein (MIND) Secondary metabolism - Terpenoids Secondary metabolism - Terpenoids division-related factor MinD gmm:31.2.5 MIND1 AT5G24020 HC-Pro|PAA2 Complex Degradation - Ubiquitination Degradation - Ubiquitination PAA2[AT2G05840] PlantCoding PAA2 fc00122 Degradation - Ubiquitination Degradation - Ubiquitination 20S proteasome alpha subunit A gmm:29.5.11.20,nuccore:af043519,omid:9611183,doi:10.1093/genetics/149.2.677 PAA AT2G05840 HC-Pro|PBB2 Complex Degradation - Ubiquitination Degradation - Ubiquitination PBB2[AT5G40580] PlantCoding PBB2 fc00125 Degradation - Ubiquitination Degradation - Ubiquitination 20S proteasome beta subunit B gmm:29.5.11.20,nuccore:af043531 PBB AT5G40580 NPR1|TGA Complex Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) NPR1[AT1G64280] PlantCoding NPR1 fc00115 This gene is a key regulator of the salicylic acid (SA)-mediated systemic acquired resistance (SAR) pathway. Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) nonexpresser of PR genes gmm:27.3.61 NPR AT1G64280 TGA[AT1G08320,AT3G12250,AT5G06950,AT5G06960] PlantCoding TGA fc00154 TGA6 encodes a basic leucine zipper transcription factor involved in the activation of SA-responsive genes. TGA2 interacts with NPR1 and may regulate PR gene expression. TGA5encodes a basic leucine zipper (B-ZIP) containing protein that interacts with NPR1 to promote expression of salicylic acid induced genes. Binds the ocs-element. Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) TGACG sequence-specific binding protein gmm:27.3.35 TGA AT3G12250,AT5G06960,AT5G06950,AT1G08320 NPR1 high & JAZ low Condition High NPR1 activity, low JAZ activity doi:10.3389/fpls.2015.00170,pmid:25859252 f(NPR1, JAZ)=(|NPR1|>t) * (|JAZ|t) * (|JAZ|>t) D14[AT3G03990] PlantCoding D14 fc00054 D14; Strigolactone esterase D14; α/β hydrolase DWARF14. D14 is the SL receptor Hormone - Strigolactones (SL) Hormone - Strigolactones (SL) alpha/beta-Hydrolases superfamily protein gmm:26.3.5 α/β hydroxylase AT3G03990 MeCLA Metabolite Hormone - Strigolactones (SL) Hormone - Strigolactones (SL) Methyl carlactonoate chebi:194506,pubchem:163488489 RANGAP|Rx Complex Signalling - Perception and resistance genes Signalling - Perception and resistance genes Rx[unknown] PlantAbstract Rx fc00196 Signalling - Perception and resistance genes Signalling - Perception and resistance genes R-gene RANGAP[AT3G63130] PlantCoding RANGAP fc00134 GTPase activator for the nuclear Ras-related regulatory protein Ran, converting it to the putatively inactive GDP-bound state. Signalling - Perception and resistance genes Signalling - Perception and resistance genes RAN GTPase activating protein doi:10.1105/tpc.113.111658,gmm:30.5 RANGAP AT3G63130 GPAphid2|RANGAP Complex Signalling - Perception and resistance genes Signalling - Perception and resistance genes GPAphid2[unknown] PlantAbstract GPAphid2 fc00002 Signalling - Perception and resistance genes Signalling - Perception and resistance genes GREEN PEACH APHID2 R-gene SOC1[AT2G45660] PlantCoding SOC1 fc00396 Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) AT2G45660 HC-Pro|PBE1 Complex Degradation - Ubiquitination Degradation - Ubiquitination PBE1[AT1G13060] PlantCoding PBE1 fc00126 Degradation - Ubiquitination Degradation - Ubiquitination 20S proteasome beta subunit E gmm:29.5.11.20,nuccore:af043536 PBE AT1G13060 OBE1|WRKY17 Complex Regulation - Transcription & Translation Regulation - Transcription & Translation,Signalling - Perception and resistance genes WRKY17[AT2G24570] PlantCoding WRKY17 fc00163 Calmodulin binding. Regulation - Transcription & Translation Regulation - Transcription & Translation WRKY family transcription factor 17 gmm:27.3.32 WRKY AT2G24570 OBE1|WRKY11 Complex Regulation - Transcription & Translation Regulation - Transcription & Translation,Signalling - Perception and resistance genes WRKY11[AT4G31550] PlantCoding WRKY11 fc00162 Calmodulin binding. Regulation - Transcription & Translation Regulation - Transcription & Translation WRKY family transcription factor 11 gmm:27.3.32 WRKY AT4G31550 CO|OBE1 Complex Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis CO[AT5G15840,SOTUB02G033400.1.1] PlantCoding CO fc00285 constans transcription factor. Encodes a protein showing similarities to zinc finger transcription factors, involved in regulation of flowering under long days. Acts upstream of FT and SOC1.; Plays a role in the regulation of flowering time by acting on 'SUPPRESSOR OF OVEREXPRESSION OF CO1', 'TERMINAL FLOWER 1' and 'FLOWERING LOCUS T'. Also regulates P5CS2 and ACS10 (involved in proline and ethylene biosynthesis, respectively). Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis B-box type zinc finger protein with CCT domain-containing protein gmm:27.3.7 CO AT5G15840 SOTUB02G033400.1.1 COI1|RBC Complex Hormone - Jasmonate (JA) Hormone - Jasmonate (JA),Primary metabolism - Photosynthesis COI1[AT2G39940] PlantCoding COI1 fc00047 RNI-like superfamily protein. Assembles SCF COI1 ubiquitin-ligase complexes in planta. A single amino acid substitution in the F-box motif of COI1 abolishes the formation of the SCF(COI1) complexes and results in loss of the JA response. Required for wound- and jasmonates-induced transcriptional regulation. Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) Coronatine insensitive 1 gmm:29.5.11.4.3.2 COI1 AT2G39940 JAZ|RBC Complex Hormone - Jasmonate (JA) Hormone - Jasmonate (JA),Primary metabolism - Photosynthesis JAZ[AT1G17380,AT1G19180,AT1G30135,AT1G48500,AT1G70700,AT1G72450,AT1G74950,AT2G34600,AT3G17860,AT3G43440,AT5G13220,AT5G20900] PlantCoding JAZ fc00088 Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) jasmonate-zim-domain protein gmm:17.7.2,doi:10.1105/tpc.111.089300 JAZ AT1G17380,AT1G19180,AT1G30135,AT1G48500,AT1G70700,AT1G72450,AT1G74950,AT2G34600,AT3G17860,AT3G43440,AT5G13220,AT5G20900 GAPC2|VPg Complex GAPC2[AT1G13440],VPg GAPC2[AT1G13440] PlantCoding GAPC2 fc00365 glyceraldehyde-3-phosphate dehydrogenase C2 AT1G13440 AT3G17020|VPg Complex AT3G17020[AT3G17020],VPg AT3G17020[AT3G17020] PlantCoding AT3G17020 fc00371 Adenine nucleotide alpha hydrolases-like superfamily protein AT3G17020 HEN1[AT4G20910] PlantCoding HEN1 fc00333 HEN1 is a methyltransferase that methylates miRNAs and siRNAs on the ribose of the last nucleotide. The 3'-end methylation probably protects the 3' ends of the small RNAs from uridylation. Regulation - Silencing Regulation - Silencing HUA ENHANCER 1 gmm:27.1.21,doi:10.1016/S0960-9822(03)00293-8 AT4G20910 DELLA[AT1G14920,AT1G66350,AT2G01570,AT3G03450,AT5G17490] PlantCoding DELLA fc00056 GA signalling cascade is composed of GA receptors (GIDa/b/c), DELLA repressor proteins and F-box proteins which control the stability of DELLA. Structurally, DELLA belong to the GRAS family of transcriptional regulators, with the DELLA motif (not present in other GRAS family members). Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes. In contrast to RGA, it is less sensitive to GA; The protein undergoes degradation in response to GA via the 26S proteasome. GAI may be involved in reducing ROS accumulation in response to stress by up-regulating the transcription of superoxide dismutases. RGL1 may be involved in reducing ROS accumulation in response to stress by up-regulating the transcription of superoxide dismutases. Rapidly degraded in response to GA. Promotes the biosynthesis of abscisic acid (ABA), especially in seed coats to maintain seed dormancy. Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) GRAS transcription factor family protein gmm:27.3.21 DELLA AT1G14920,AT3G03450,AT5G17490,AT1G66350,AT2G01570 PUB15[AT5G42340] PlantCoding PUB15 fc00343 Plant U-Box 15 AT5G42340 N-pyruvoyl-L-Glu Metabolite Byproduct of SA biosynthesis Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) N-pyruvoyl-L-glutamate metacyc:cpd-24913,chebi:195520 SA Metabolite Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) Salicylic acid chebi:16914,chebi:30762 IsoChor-9-Glu Metabolite Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) Isochorismoyl-L-glutamate metacyc:cpd-24912,chebi:195519 EPS1[AT5G67160] PlantCoding EPS1 fc00138 Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) HXXXD-type acyl-transferase family protein gmm:16.2 AT5G67160 GST[AT1G02920,AT1G02930,AT1G17170,AT2G02930,AT2G47730,AT4G02520] PlantCoding GST fc00081 Detoxification. Actually implicated in early response (glutathione S-transferase). Signalling - Reactive oxygen species (ROS) Signalling - Reactive oxygen species (ROS) glutathione S-transferase pmid:20198573,pmid:12897257,pmid:14576289,pmid:8090746,gmm:26.9 GST AT1G02920,AT1G02930,AT1G17170,AT2G02930,AT2G47730,AT4G02520 BAK1|FLS2|flg22 Complex Hormone - Brassinosteroids (BS) Hormone - Brassinosteroids (BS) flg22 ForeignCoding Flagellin is the structural protein that forms the major portion of flagellar filaments; this is the 22 amino acids flagellin peptide known as flg22 (spans 22 amino acids in the core of the conserved domain). Flagellins from different bacterial species vary in their central part but show conservation of their N-terminal and C-terminal regions. Stress - Biotic Stress - Biotic flagellin fragment bacteria BAK1[AT4G33430] PlantCoding BAK1 fc00033 Brassinosteroids Hormone - Brassinosteroids (BS) Hormone - Brassinosteroids (BS) BRI1-associated receptor kinase; somatic embryogenesis receptor-like kinase 3 gmm:20.1.2,gmm:30.2.2 LRR-BAK1 AT4G33430 FLS2[AT5G46330] PlantCoding FLS2 fc00076 Encodes a leucine-rich repeat serine/threonine protein kinase that is expressed ubiquitously. FLS2 is involved in MAP kinase signalling relay involved in innate immunity. Essential in the perception of flagellin, a potent elicitor of the defense response. FLS2 is directed for degradation by the bacterial ubiquitin ligase AvrPtoB. The mRNA is cell-to-cell mobile. Signalling - Perception and resistance genes Signalling - Perception and resistance genes Leucine-rich receptor-like protein kinase family protein; PRR protein flagellin sensing 2 gmm:30.2.12,tair:locus:2170483 LRR-FLS2 AT5G46330 MKS1|WRKY33 Complex Signalling - MAP kinases (MAPKs) Signalling - MAP kinases (MAPKs) WRKY33[AT2G38470] PlantCoding WRKY33 fc00166 Regulation - Transcription & Translation Regulation - Transcription & Translation WRKY family transcription factor 33 gmm:27.3.32 WRKY AT2G38470 MKS1[AT3G18690] PlantCoding MKS1 fc00104 Encodes a nuclear-localized member of a plant specific gene family involved in mediating responses to pathogens. Interacts with WRKY transcriptional regulators. Signalling - MAP kinases (MAPKs) Signalling - MAP kinases (MAPKs) mitogen-activated protein (MAP) kinase substrate 1 gmm:20.1.3 MKS1 AT3G18690 CI|PSAK Complex Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis PSAK[AT1G30380] PlantCoding PSAK fc00133 Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis photosystem I subunit K gmm:1.1.2.2 PSAK AT1G30380 GA|GID1 Complex Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) GA Metabolite active forms (gibberellin A1, gibberellin A3, gibberellin A4) Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) Gibberellins chebi:28833,chebi:27717,chebi:32902 GID[AT3G05120,AT3G63010,AT4G24210,AT5G27320,LOC_OS02G36974,LOC_OS05G33730] PlantCoding GID fc00305 Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) gibberellin (GA) receptor gmm:17.6.2 GID AT3G05120,AT3G63010,AT4G24210,AT5G27320 LOC_OS02G36974,LOC_OS05G33730 GA|GID1|SLR1 Complex Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) SLR1[LOC_OS06G03710] PlantCoding SLR1 fc00150 Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) transcriptional repressor of the gibberellin (GA) signaling pathway gmm:15.5.12,plaza:os06t0127800 DELLA LOC_OS06G03710 DELLA|GA|GID1 Complex Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) ESP|WRKY53 Complex Regulation - Transcription & Translation Regulation - Transcription & Translation,Signalling - Perception and resistance genes ESP[AT1G54040] PlantCoding ESP fc00073 Antagonistically interacts with WRKY53. Involved in pathogen resistance and leaf senescence. Modulated by JA and SA equilibrium. Signalling - Perception and resistance genes Signalling - Perception and resistance genes enzyme regulator (epithiospecifier protein) gmm:16.5.1.3.2 ESP/NSP AT1G54040 WRKY53[AT4G23810] PlantCoding WRKY53 fc00169 Regulation - Transcription & Translation Regulation - Transcription & Translation WRKY family transcription factor 53 gmm:27.3.32,doi:10.1105/tpc.106.042705 WRKY AT4G23810 WRKY30|WRKY53 Complex Regulation - Transcription & Translation Regulation - Transcription & Translation WRKY30[AT5G24110] PlantCoding WRKY30 fc00165 Regulation - Transcription & Translation Regulation - Transcription & Translation WRKY family transcription factor 30 gmm:27.3.32 WRKY AT5G24110 JAZ|WRKY57 Complex Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) WRKY57[AT1G69310] PlantCoding WRKY57 fc00170 Regulation - Transcription & Translation Regulation - Transcription & Translation WRKY family transcription factor 57 gmm:27.3.32 WRKY AT1G69310 AUX/IAA|WRKY57 Complex Hormone - Auxins (AUX) Hormone - Auxins (AUX) AUX/IAA[AT1G04100,AT1G04240,AT1G04250,AT1G04550,AT1G15050,AT1G15580,AT1G51950,AT1G52830,AT1G80390,AT2G01200,AT2G22670,AT2G33310,AT2G46990,AT3G04730,AT3G15540,AT3G16500,AT3G17600,AT3G23030,AT3G23050,AT3G62100,AT4G14550,AT4G14560,AT4G28640,AT4G29080,AT4G32280,AT5G25890,AT5G43700,AT5G57420,AT5G65670] PlantCoding AUX/IAA fc00136 JA-induced leaf senescence; auxin-responsive protein IAA29; Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression. Hormone - Auxins (AUX) Hormone - Auxins (AUX) indole-3-acetic acid inducible gmm:17.2.3,gmm:27.3.40 IAA29 AT1G04100,AT1G04240,AT1G04250,AT1G04550,AT1G15050,AT1G15580,AT1G51950,AT1G52830,AT1G80390,AT2G01200,AT2G22670,AT2G33310,AT2G46990,AT3G04730,AT3G15540,AT3G16500,AT3G17600,AT3G23030,AT3G23050,AT3G62100,AT4G14550,AT4G14560,AT4G28640,AT4G29080,AT4G32280,AT5G25890,AT5G43700,AT5G57420,AT5G65670 SCL14|TGA Complex Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) SCL14[AT1G07530] PlantCoding SCL14 fc00147 GRAS family transcription factor. The protein interacts with the TGA2 transcription factor and affects the transcription of stress-responsive genes. Probable transcription factor involved in plant development. Regulation - Transcription & Translation Regulation - Transcription & Translation scarecrow-like 14; GRAS family transcription factor gmm:27.3.21 GRAS AT1G07530 DELLA|JAZ Complex Hormone - Gibberellin (GA) Hormone - Gibberellin (GA),Hormone - Jasmonate (JA) DELLA|MYC Complex Hormone - Gibberellin (GA) Hormone - Gibberellin (GA),Hormone - Jasmonate (JA) MYC2[AT1G32640] PlantCoding MYC2 fc00108 MYC2, MYC3, MYC4 are JAZ-interacting transcription factors (with a typical DNA binding domain of a basic helix-loop-helix leucine zipper motif) that act together to control jasmonate-related defense responses. MYC2 binds to an extended G-Box promoter motif and interacts with Jasmonate ZIM-domain proteins. Related bHLH TFs MYC3 and MYC4 also regulate both overlapping and distinct MYC2-regulated functions in Arabidopsis while MYC2 orthologs act as 'master switches' that regulate JA-mediated biosynthesis of secondary metabolites. Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) basic helix-loop-helix (bHLH) DNA-binding superfamily protein gmm:27.3.6 MYC AT1G32640 GID|SCF Complex Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) SCF Complex Degradation - Ubiquitination Degradation - Ubiquitination SCF go:0019005 CAT|LSD1 Complex Signalling - Reactive oxygen species (ROS) Signalling - Cell death,Signalling - Reactive oxygen species (ROS) LSD1[AT4G20380] PlantCoding LSD1 fc00097 Regulation - Transcription & Translation Regulation - Transcription & Translation LSD1 zinc finger family protein gmm:27.3.99 LSD1 AT4G20380 CAT[AT1G20620,AT1G20630,AT4G35090,SOTUB12G027890.1.1] PlantCoding CAT fc00191 Catalase, catalyzes the breakdown of hydrogen peroxide (H2O2) into water and oxygen. Catalyzes the reduction of hydrogen peroxide using heme group as cofactor. Loss of function mutations have increased H2O2 levels and increased H2O2 sensitivity. Signalling - Reactive oxygen species (ROS) Signalling - Reactive oxygen species (ROS) catalase gmm:21.6,doi:10.1093/jxb/erq282 CAT AT1G20620,AT1G20630,AT4G35090 SOTUB12G027890.1.1 ACX[AT1G06290,AT2G35690,AT4G16760,AT5G65110,SOTUB10G008540.1.1] PlantCoding ACX fc00184 Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) acyl-CoA oxidase ec:1.3.3.6,kegg:k00232,gmm:11.9.4.2,doi:10.1007/978-0-387-85498-4_8 ACX AT1G06290,AT2G35690,AT4G16760,AT5G65110 SOTUB10G008540.1.1 D14|MAX2|SCF Complex Hormone - Strigolactones (SL) Hormone - Strigolactones (SL) MAX2[AT2G42620] PlantCoding MAX2 fc00100 MAX2 binds to the activated D14 to induce SL-mediated ubiquitination (signalling). Signalling - Perception and resistance genes Signalling - Perception and resistance genes E3 ubiquitin ligase SCF complex F-box subunit; more axillary branches 2 gmm:29.5.11.4.3.2 F-box/LRR-repeat AT2G42620 tRNA-adenine Metabolite Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) Adenosine in tRNA chebi:17843,kegg:C17324,metacyc:tRNA-Adenosines-37 IPT2,9[AT2G27760,AT5G20040] PlantCoding IPT2,9 fc00358 Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) tRNA isopentenyltransferases gmm:17.4.1,ec:2.5.1.75,doi:10.1073/pnas.0603522103 IPT AT2G27760,AT5G20040 DMAPP Metabolite Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) dimethylallyl diphosphate chebi:16057,kegg:C00235,metacyc:CPD-4211 prenyl-tRNA Metabolite Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) tRNA containing 6-isopentenyladenosine kegg:c04432 ADK[AT3G09820,AT5G03300] PlantCoding ADK fc00015 Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) adenosine kinase 1,2 ec:2.7.1.20,gmm:23.3.2.1 ADK AT5G03300,AT3G09820 cZ-ribotide Metabolite Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) cis-zeatin riboside monophosphate chebi:80493 cZ-riboside Metabolite Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) cis-zeatin riboside chebi:20833 UGT[AT1G22400,AT2G36750,AT2G36800,AT5G05860,AT5G05870] PlantCoding UGT fc00157 UGT76C1 and UGT76C2 recognized all cytokinins and glucosylated the hormones at the N7 and N9 positions. UGT85A1, UGT73C5, and UGT73C1 recognized trans-zeatin and dihydrozeatin, which have an available hydroxyl group for glucosylation and formed the O-glucosides. Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) trans-Zeatin glycosyltransferases doi:/10.1074/jbc.M409569200,gmm:26.2,ec:2.4.1.118,ec:2.4.1.203 UGT AT2G36750,AT2G36800,AT1G22400,AT5G05860,AT5G05870 cZ-glucosides Metabolite Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) cis-zeatin glucosides chebi:133211,chebi:133208,chebi:29043,pubchem:404609500,kegg:c15546 UDP-Glc Metabolite Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) UDP-α-D-glucose chebi:46229 cZ Metabolite Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) cis-zeatin chebi:46570 TIP1-2|VPg Complex TIP1-2[AT3G26520],VPg TIP1-2[AT3G26520] PlantCoding TIP1-2 fc00368 tonoplast intrinsic protein 2 AT3G26520 DZ-ribotide Metabolite Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) dihydrozeatin riboside monophosphate chebi:80496 DZ-riboside Metabolite Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) dihydrozeatin riboside chebi:80498 AHK2,3,4[AT1G27320,AT2G01830,AT5G35750] PlantCoding AHK2,3,4 fc00018 CK receptor Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) histidine kinase 2,3,4 ec:2.7.13.3,gmm:17.4.2 AHK AT5G35750,AT1G27320,AT2G01830 tZ Metabolite Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) trans-zeatin; [6-((E)-4-hydroxy-3-methylbut-2-enylamino)purine] chebi:16522 DZ Metabolite Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) dihydrozeatin chebi:17874 iP Metabolite Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) N6-isopentenyladenine chebi:17660 SAMe Metabolite Hormone - Ethylene (ET) Hormone - Ethylene (ET) S-adenosyl-L-methionine chebi:15414 L-Met Metabolite Hormone - Ethylene (ET) Hormone - Ethylene (ET) L-methionine chebi:16643 NIMIN|NPR1 Complex Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) NIMIN[AT1G02450,AT1G09415,AT3G25882] PlantCoding NIMIN fc00114 Encodes a kinase that physically interacts with NPR1/NIM1. NIMIN1 modulates PR gene expression according the following model: NPR1 forms a ternary complex with NIMIN1 and TGA factors upon SAR induction that binds to a positive regulatory cis-element of the PR-1 promoter, termed LS7. This leads to PR-1 gene induction. Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) NIM1-interacting gmm:27.3.99 NIMIN AT1G09415,AT3G25882,AT1G02450 ACC Metabolite An alpha-amino-acid anion resulting from the deprotonation of the carboxy group of 1-aminocyclopropanecarboxylic acid. Direct precursor of ethylene. Hormone - Ethylene (ET) Hormone - Ethylene (ET) 1-aminocyclopropane-1-carboxylate chebi:30526,pubchem:5460234,kegg:c01234,doi:10.3389/fpls.2014.00640 ACS[AT1G01480,AT2G22810,AT3G49700,AT3G61510,AT4G08040,AT4G11280,AT4G26200,AT4G37770,AT5G65800] PlantCoding ACS fc00009 Hormone - Ethylene (ET) Hormone - Ethylene (ET) 1-aminocyclopropane-1-carboxylic acid (ACC) synthase ec:4.4.1.14,gmm:17.5.1.1 ACS AT1G01480,AT2G22810,AT3G49700,AT3G61510,AT4G08040,AT4G11280,AT4G26200,AT4G37770,AT5G65800 ET Metabolite Hormone - Ethylene (ET) Hormone - Ethylene (ET) Ethylene chebi:18153 ACO[AT1G05010,AT1G12010,AT1G62380,AT1G77330,AT2G19590,SOTUB07G018820.1.1] PlantCoding ACO fc00008 Ethylene-forming enzyme. ACOs belong to a large family of dioxygenases that require iron (Fe2+) as co-factor and bicarbonate as activator (HOM03D000012). Expression of the AtACO2 transcripts is affected by ethylene. Hormone - Ethylene (ET) Hormone - Ethylene (ET) 1-aminocyclopropane-1-carboxylic acid (ACC) oxidase gmm:17.5.1.2,ec:1.14.17.4 ACO AT1G77330,AT1G05010,AT1G62380,AT1G12010,AT2G19590 SOTUB07G018820.1.1 ROS Metabolite Family of ROS compounds, including: hydrogen peroxide, hydroperoxyl radical, superoxide anion, ozone, hydroxyl radical Signalling - Reactive oxygen species (ROS) Signalling - Reactive oxygen species (ROS) Reactive oxygen species chebi:16240,chebi:25935,chebi:18421,chebi:25812,chebi:29191 MDA Metabolite Malonaldehyde (MDA) occurs widely in biological systems undergoing severe oxidative stress. Prolonged exposure of Arabidopsis resulted in damage to leaf tissue. Hormone - Jasmonate (JA) Hormone - Jasmonate (JA),Stress - Biotic,Signalling - Reactive oxygen species (ROS) Malondialdehyde kegg:c19440,pubchem:10964,chebi:566274,metacyc:cpd-21542,doi:10.1111/j.1365-313X.2000.00897.x ALA Metabolite Essential fatty acid processes. Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) α-linolenic-acid chebi:27432,kegg:c06427 Ile Metabolite amino acid Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) Isoleucine chebi:58045 Thr Metabolite amino acid Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) Threonine chebi:57926 OMR1[AT3G10050] PlantCoding OMR1 fc00117 Threonine deaminase (TD) in nbe. First enzyme in the biosynthetic pathway of isoleucine. Catalyzes the formation of alpha-ketobutyrate from threonine in a two-step reaction. Important in defense against insects -reduced pool of Thr or for the synthesis of JA-Ile Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) threonine ammonia-lyase gmm:13.1.4.5.1 OMR AT3G10050 13-HPOT Metabolite parallel path to OPDA (jasmonic acid biosynthesis) Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) 13(S)-hydroperoxylinolenic acid chebi:48905,chebi:58757,kegg:C04785,pubchem:45266757,metacyc:CPD-725 LOX[AT1G17420,AT1G55020,AT1G67560,AT1G72520,AT3G22400,AT3G45140,SOTUB03G034620.1.1] PlantCoding LOX fc00096 lipoxygenase Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) lipoxygenase gmm:17.7.1.2,kegg:k00454,kegg:k15718,kegg:k00454,kegg:k00454,kegg:k15718,kegg:k00454,ec:1.13.11.12,ec:1.13.11.58 LOX AT1G55020,AT1G17420,AT1G67560,AT1G72520,AT3G22400,AT3G45140 SOTUB03G034620.1.1 12,13-EOT Metabolite parallel path to OPDA (jasmonic acid biosynthesis) Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) 12,13(S)-epoxylinolenic acid chebi:15653,metacyc:CPD-728 AOS[AT5G42650] PlantCoding AOS fc00022 allene oxide synthase Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) hydroperoxide dehydratase kegg:k01723,ec:4.2.1.92,gmm:17.7.1.3 AOS AT5G42650 OPDA Metabolite parallel path to OPDA (jasmonic acid biosynthesis) Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) 12-oxophytodienoic acid chebi:34005,pubchem:45266620,metacyc:CPD-729 AOC[AT1G13280,AT3G25760,AT3G25770,AT3G25780] PlantCoding AOC fc00021 Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) allene oxide cyclase 1,2,3,4 kegg:k10525,ec:5.3.99.6,gmm:17.7.1.4 AOC AT3G25770,AT1G13280,AT3G25780,AT3G25760 OPC8 Metabolite Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) oxopentenyl-cyclopentane-octanoic acid pubchem:25244083 OPR[AT1G76680,AT1G76690,AT2G06050] PlantCoding OPR fc00119 OPR3: the only member of a small family of related enone reductases accepting the (9S,13S)-enantiomer of OPDA. Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) 12-oxophytodienoic acid reductase gmm:17.7.1.5,kegg:k05894,ec:1.3.1.42 OPR AT1G76680,AT1G76690,AT2G06050 R-gene|potyvirus Complex Signalling - Perception and resistance genes Signalling - Perception and resistance genes potyvirus ForeignEntity Stress - Biotic Stress - Biotic Potyvirus is a genus of ssRNA(+) virus in the family Potyviridae. ncbitaxon:12195 virus TNL[unknown] PlantAbstract TNL fc00004 Arabidopsis identifiers include AT5G66900 Signalling - Perception and resistance genes Signalling - Perception and resistance genes Toll/Interleukin-1 receptor (TIR)-NLRs doi:10.1101/2021.02.25.431980 R-gene ASK[AT1G06390,AT1G75950,AT5G42190] PlantCoding ASK fc00188 SKP1 is a core component of the SCF family of E3 ubiquitin ligases and serves to tether the rest of the complex to an F-box protein, which provides specificity in binding to ubiquitin ligase substrate proteins. Degradation - Ubiquitination Degradation - Ubiquitination S phase kinase-associated protein pmid:12172031 ASK AT1G06390,AT1G75950,AT5G42190 RBX[AT3G42830,AT5G20570] PlantCoding RBX fc00139 RING/U-box superfamily protein Degradation - Ubiquitination Degradation - Ubiquitination RING-box pmid:12172031,gmm:29.5.11.4.2 RBX AT5G20570,AT3G42830 CUL[AT1G02980,AT1G43140,AT4G02570] PlantCoding CUL fc00051 Encodes an Arabidopsis Cullin family proteins, a cullin that is a component of SCF ubiquitin ligase complexes involved in mediating responses to auxin and jasmonic acid. Degradation - Ubiquitination Degradation - Ubiquitination cullin pmid:12172031,gmm:29.5.11.4.3.3 CUL AT1G43140,AT1G02980,AT4G02570 OPC8-CoA Metabolite Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) oxopentenyl-cyclopentane-octanoyl-CoA pubchem:44237325 OPCL1[AT1G20510] PlantCoding OPCL1 fc00118 OPC8 undergoes three rounds of beta-oxidation involving three enzymes to yield (+)- 7-iso -jasmonic acid which equilibrates to the more stable (-)-JA (part 1). OPCL1: physiological role in JA biosynthesis was confirmed for only this gene. Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) OPC-8:0 CoA ligase1 gmm:16.2.1.3,kegg:k10526,ec:6.2.1.-,doi:10.1007/978-0-387-85498-4_8 4CLL AT1G20510 OPC6-CoA Metabolite Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) OPC6-CoA pubchem:44237133 MFP[AT3G06860,AT3G15290,AT4G29010] PlantCoding MFP fc00102 experimental evidence. OPC8 undergoes three rounds of beta-oxidation involving three enzymes to yield (+)- 7-iso -jasmonic acid which equilibrates to the more stable (-)-JA (part 3). Hormone - Jasmonate (JA) Hormone - Jasmonate (JA),Hormone - Salicylic acid (SA) enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase gmm:11.9.4.9,ec:4.2.1.17,ec:1.1.1.35,ec:1.1.1.211,kegg:k10527,aracyc:ohacyl-coa-dehydrog-rxn,doi:10.1007/978-0-387-85498-4_8,metacyc:at4g29010-monomer MFP AT3G06860,AT3G15290,AT4G29010 OPC4-CoA Metabolite Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) OPC4-CoA pubchem:44237211 JA-CoA Metabolite Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) jasmonoyl-CoA pubchem:44237154 KAT[AT1G04710,AT2G33150,AT5G48880] PlantCoding KAT fc00092 peroxisomal 3-ketoacyl-CoA thiolase Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) acetyl-CoA acyltransferase ec:2.3.1.16,aracyc:rxn-20153 KAT AT1G04710,AT2G33150,AT5G48880 JA Metabolite (+)-7-iso-jasmonate (interconverted through spontaneous epimerization) Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) Jasmonic acid pubchem:25245750,chebi:18292 ACH[AT2G30720,AT5G48370] PlantCoding ACH fc00007 Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) thioesterase/thiol ester dehydrase-isomerase superfamily protein ec:3.1.2.-,aracyc:acyl-coa-hydrolase-rxn ACH AT2G30720,AT5G48370 MeJA Metabolite (-)-jasmonic acid methyl ester Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) methyl jasmonic acid pubchem:5367719 JMT[AT1G19640] PlantCoding JMT fc00089 Belongs to a PLAZA-dicots_v3 family, which contains also genes similar to SAMT (turns SA into MeSA and GA into MeGA; among others). Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) jasmonate O-methyltransferase gmm:17.8.1.1.7,ec:2.1.1.141,aracyc:at1g19640-monomer JMT AT1G19640 JA-Ile Metabolite (-)-jasmonoyl-L-isoleucine (the non-active form; epimerization) Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) Jasmonoyl-isoleucine pubchem:54758681 JAR[AT2G46370,AT4G03400] PlantCoding JAR fc00087 JAR1 is the enzyme responsible for the conjugation of JA with isoleucine (JA-Ile). GH family in KEGG (K14487) contains additional 17 members to this one. Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) Auxin-responsive GH3 family protein gmm:33.99 JAR AT4G03400,AT2G46370 12-OH-JA-Ile Metabolite Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) 12-hydroxyjasmonic acid 12-O-β-D-glucoside chebi:136181,metacyc:cpd-13420 CYP94[AT2G27690,AT3G48520] PlantCoding CYP94 fc00053 CYP94B3 is a jasmonoyl-isoleucine-12-hydroxylase that catalyzes the formation of 12-OH-JA-Ile from JA-Ile. Gene expression is induced in response to wounding and jasmonic acid treatment. Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) cytochrome P450, family 94, subfamily C, polypeptide 1,3 gmm:26.1 CYP94 AT2G27690,AT3G48520 MeSA Metabolite Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) methyl salicylate chebi:31832 MES[AT2G23560,AT2G23580,AT2G23600,AT2G23620,AT4G37150,PGSC0003DMG400000756,SOTUB02G012040.1.1] PlantCoding MES fc00101 MES(1,2,4,7,9) appears to be involved in MeSA hydrolysis in planta. Expression of MES7, MES9 can restore systemic acquired resistance in SAR-deficient tobacco plants. MES4 encodes a protein shown to have carboxylesterase activity and methyl salicylate esterase activity in vitro. Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) methyl esterase 1,2,4,7,9 gmm:26.8 MES AT2G23560,AT2G23580,AT2G23600,AT2G23620,AT4G37150 PGSC0003DMG400000756,SOTUB02G012040.1.1 OBE2|VPg Complex Signalling - Growth Signalling - Growth,Stress - Biotic OBE2[AT5G48160] OBE2[AT5G48160] PlantCoding OBE2 fc00344 Signalling - Growth Signalling - Growth potyvirus VPg interacting protein (DUF1423) AT5G48160 IsoChor Metabolite Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) Isochorismate chebi:29780 Chor Metabolite Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) Chorismate chebi:29748 ICS[AT1G18870,AT1G74710] PlantCoding ICS fc00084 Encodes a protein with isochorismate synthase activity. Mutants fail to accumulate salicylic acid. Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) isochorismate synthase gmm:18.5.2.1 ICS AT1G18870,AT1G74710 Prep Metabolite Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) prephenate chebi:57852 CM[AT1G69370,AT3G29200,AT5G10870] PlantCoding CM fc00044 Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) chorismate mutase 1,2,3 gmm:13.1.6.2.1 CM AT3G29200,AT1G69370,AT5G10870 Phe Metabolite Hormone - Salicylic acid (SA) Primary metabolism - Amino-acids,Hormone - Salicylic acid (SA) Phenylalanine chebi:28044,chebi:17295,pubchem:6140,metacyc:phe PAL[AT2G37040,AT3G10340,AT3G53260,AT5G04230] PlantCoding PAL fc00124 PAL4, a putative a phenylalanine ammonia-lyase. PAL3 differs significantly from PAL1 and PAL2 and other sequenced plant PAL genes. Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) phenylalanine ammonia-lyase 1,2,3,4 gmm:16.2.1.1 PAL AT5G04230,AT3G53260,AT2G37040,AT3G10340 MYC|PYL Complex Hormone - Jasmonate (JA) Hormone - Jasmonate (JA),Hormone - Abscisic acid (ABA) PYL6[AT2G40330],MYC2[AT1G32640] PYL[AT1G01360,AT2G40330] PlantCoding PYL fc00313 Functions as abscisic acid sensor. Signalling - Perception and resistance genes Hormone - Abscisic acid (ABA),Signalling - Perception and resistance genes regulatory components of ABA receptor family protein gmm:20.1 AT1G01360,AT2G40330 SAMC[AT1G34065,AT4G39460] PlantCoding SAMC fc00145 SAMC1 encodes a plastid metabolite transporter required for the import of S-Adenosylmethionine from the cytosol. Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) S-adenosylmethionine carrier 1,2 gmm:34.9 SAMC AT1G34065,AT4G39460 ATG1A[AT3G61960] PlantCoding ATG1A fc00331 Degradation - Autophagy Degradation - Autophagy Protein kinase superfamily protein pmid:21984698,doi:10.1105/tpc.111.090993 AT3G61960 SAG Metabolite Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) salicylic acid 2-O-β-D-glucoside chebi:145663 SAGT[AT2G43820,AT2G43840] PlantCoding SAGT fc00143 Induced by Salicylic acid, virus, fungus and bacteria. Involved in the tryptophan synthesis pathway. UGT74F1 transfers UDP:glucose to salicylic acid (forming a glucoside), benzoic acid, quercetin, and athranilate in vitro. Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) UDP-glucosyltransferase gmm:26.2 SAGT AT2G43840,AT2G43820 SOD[AT1G08830,AT1G12520,AT2G28190,AT3G56350,AT5G18100] PlantCoding SOD fc00151 Copper/zinc superoxide dismutase. CSD1 encodes a cytosolic copper/zinc superoxide dismutase that can detoxify superoxide radicals. Its expression is affected by miR398-directed mRNA cleavage. Regulated by biotic and abiotic stress. CCS encodes copper chaperone for SOD1 (delivers copper to the Cu-Zn superoxide dismutase). CSD2 can detoxify superoxide radicals. SOD is a iron/manganese superoxide dismutase. CSD3 is a putative peroxisomal CuZnSOD inducible by a high-light pulse. Signalling - Reactive oxygen species (ROS) Signalling - Reactive oxygen species (ROS) superoxide dismutase gmm:21.6,gmm:15.2 SOD AT5G18100,AT1G12520,AT3G56350,AT1G08830,AT2G28190 O2 Metabolite ROS precursors Signalling - Reactive oxygen species (ROS) Signalling - Reactive oxygen species (ROS) Oxygen chebi:25805 RBOH[AT1G09090,AT1G19230,AT1G64060,AT3G45810,AT4G11230,AT4G25090,AT5G07390,AT5G47910,AT5G51060,AT5G60010,SOTUB06G025550.1.1,SOTUB06G025580.1.1,SOTUB08G028720.1.1] PlantCoding RBOH fc00315 Respiratory burst oxidase. NADPH-oxidase RBOHB plays a role in seed after-ripening. Major producer of superoxide in germinating seeds. RBOHF interacts with RBOHD to fine tune the spatial control of ROI production and hypersensitive response to cell in and around infection site. RBOHC is required for the production of reactive oxygen species in response to extracellular ATP stimulus. The increase in ROS production stimulates Ca2+ influx. Signalling - Reactive oxygen species (ROS) Signalling - Reactive oxygen species (ROS) NADPH oxidase doi:10.1104/pp.103.024208,gmm:9.2,gmm:20.1.1 NADPH-dehydrogenase AT5G60010,AT5G51060,AT5G47910,AT5G07390,AT4G25090,AT4G11230,AT3G45810,AT1G64060,AT1G19230,AT1G09090 SOTUB06G025550.1.1,SOTUB06G025580.1.1,SOTUB08G028720.1.1 e- Metabolite Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis electron chebi:10545 CO2-deficiency Process Signalling - Reactive oxygen species (ROS) Signalling - Reactive oxygen species (ROS) ROS processes. conceptual:process ent-Copalyl-PP Metabolite Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) ent-Copalyl diphosphate chebi:58553,kegg:c00353 Geranylgeranyl-PP Metabolite Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) Geranylgeranyl diphosphate pubchem:3646,chebi:447277,kegg:c00353 CPS[AT4G02780,SOTUB06G034690.1.1] PlantCoding CPS fc00301 Terpenoid cyclases/Protein prenyltransferases superfamily protein Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) ent-copalyl diphosphate synthase gmm:17.6.1.1 CPS AT4G02780 SOTUB06G034690.1.1 ent-Kaurene Metabolite Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) ent-Kaurene chebi:15415 KS[AT1G79460] PlantCoding KS fc00094 Terpenoid cyclases/Protein prenyltransferases superfamily protein Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) ent-kaurene synthase gmm:17.6.1.2 KS AT1G79460 ent-Kaurenoic acid Metabolite Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) ent-Kaurenoic acid chebi:15417 KO[AT5G25900] PlantCoding KO fc00093 Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) ent-kaurene oxidase gmm:17.6.1.3 KO AT5G25900 GA12 Metabolite Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) gibberellin A12 chebi:30088 KAO1,2[AT1G05160,AT2G32440] PlantCoding KAO1,2 fc00091 The gibberellin biosynthetic genes AtKAO1 and AtKAO2 have overlapping roles Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) ent-kaurenoic acid oxidase 1,2 gmm:26.1 KAO AT1G05160,AT2G32440 GA9 Metabolite Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) gibberellin A9 chebi:29605 GA20ox[AT1G44090,AT1G60980,AT4G25420,AT5G07200,AT5G51810,SOTUB01G031210.1.1,SOTUB03G007160.1.1,SOTUB09G017710.1.1,SOTUB10G011620.1.1,SOTUB11G029030.1.1] PlantCoding GA20ox fc00302 Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) gibberellin 20-oxidase gmm:17.6.1.11 GA20ox AT1G44090,AT1G60980,AT4G25420,AT5G07200,AT5G51810 SOTUB01G031210.1.1,SOTUB03G007160.1.1,SOTUB09G017710.1.1,SOTUB10G011620.1.1,SOTUB11G029030.1.1 GA20 Metabolite Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) gibberellin A20 chebi:27742 GA3ox[AT1G15550,AT1G80330,AT1G80340,AT4G21690,SOTUB06G023360.1.1] PlantCoding GA3ox fc00303 Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) gibberellin 3-oxidase 1,2,3,4 gmm:17.6.1.12 GA3ox AT1G15550,AT1G80330,AT1G80340,AT4G21690 SOTUB06G023360.1.1 GA8 Metabolite Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) gibberellin A8 chebi:28861 C19-GA2ox[AT1G02400,AT1G30040,AT1G47990,AT1G78440,AT2G34555] PlantCoding C19-GA2ox fc00035 Encodes a gibberellin 2-oxidase that acts on C19 gibberellins Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) gibberellin 2-oxidase 1,2,3,4,6 gmm:17.6.1.13 GA2ox AT1G02400,AT2G34555,AT1G30040,AT1G47990,AT1G78440 GA34 Metabolite Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) gibberellin A34 chebi:29593 GA-methylester Metabolite Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) Gibberellin A1, A3, A4 methyl ester chebi:73250,chebi:73253,chebi:73252 GAMT1,2[AT4G26420,AT5G56300] PlantCoding GAMT1,2 fc00077 Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) gibberellic acid (GA) methyltransferase 1,2 gmm:17.6.1 GAMT AT4G26420,AT5G56300 9-cis-β-carotene Metabolite Hormone - Strigolactones (SL) Hormone - Strigolactones (SL),Secondary metabolism - Terpenoids 9-cis-β-carotene chebi:67188,kegg:c20484,kegg:c20484 β-Carotene Metabolite A cyclic carotene obtained by dimerisation of all-trans-retinol. A strongly-coloured red-orange pigment abundant in plants and fruit and the most active and important provitamin A carotenoid. Secondary metabolism - Terpenoids Hormone - Strigolactones (SL),Hormone - Abscisic acid (ABA),Secondary metabolism - Terpenoids all-trans-β-carotene pubchem:54603957,chebi:17579,kegg:c02094,pubchem:5178 D27[AT1G03055,OS11G0587000] PlantCoding D27 fc00046 Hormone - Strigolactones (SL) Hormone - Strigolactones (SL) beta-carotene isomerase D27-like protein β-carotene isomerase AT1G03055 OS11G0587000 CLA Metabolite Carlactone (CL) is the common precursor for all known SLs, but must be modified by cytochrome P450 enzymes of the MAX1 family to form carlactonoic acid (CLA) or other active derivatives. Hormone - Strigolactones (SL) Hormone - Strigolactones (SL) Carlactonoic acid doi:10.1186/s12915-019-0689-6,pubchem:90658468 CL Metabolite Carlactone (CL) is a compound with strigolactone-like biological activities. CL is the common precursor for all known SLs, but must be modified by cytochrome P450 enzymes of the MAX1 family to form carlactonoic acid (CLA) or other active derivatives. Hormone - Strigolactones (SL) Hormone - Strigolactones (SL) Carlactone doi:10.1186/s12915-019-0689-6,doi:10.1126/science.1218094,chebi:67190,pubchem:172232413,kegg:c20693,kegg:ath00906 MAX1[AT2G26170] PlantCoding MAX1 fc00099 Carlactone (CL), is the common precursor for all known SLs, but must be modified by cytochrome P450 enzymes of the MAX1 family to form carlactonoic acid (CLA) or other active derivatives. Hormone - Strigolactones (SL) Hormone - Strigolactones (SL) cytochrome P450, family 711, subfamily A, polypeptide 1; more axillary branches 1 gmm:26.1,doi:10.1186/s12915-019-0689-6 CYP AT2G26170 HMBDP Metabolite Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) (2E)-4-hydroxy-3-metylbut-2-enyl diphosphate chebi:15664 ISPH[AT4G34350] PlantCoding ISPH fc00085 methylerythritol phosphate pathway. Arabidopsis ISPH is involved in the plastid nonmevalonate pathway of isoprenoid biosynthesis. It was shown to complement the lethal phenotype of E. coli ispH mutant and is therefore most likely encodes a protein with 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity involved in the last step of mevalonate-independent isopentenyl biosynthesis. Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) 4-hydroxy-3-methylbut-2-enyl diphosphate reductase gmm:16.1.1.7,ec:1.17.7.4 ISPH AT4G34350 IPT1,3,4,5,6,7,8[AT1G25410,AT1G68460,AT3G19160,AT3G23630,AT3G63110,AT4G24650,AT5G19040] PlantCoding IPT1,3,4,5,6,7,8 fc00307 IPT4,6,8 are not normally expressed in the vegetative phase. This grouping draws from doi:10.1073/pnas.0603522103 (IPT1,IPT3,IPT5,IPT7 in planta), doi:10.1074/jbc.M102130200 (IPT6, IPT8, in ecoli), doi:10.1093/pcp/pce112 (IPT4, in callus). Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) ATP/ADP isopentenyltransferases gmm:17.4.1,ec:2.5.1.27,ec:2.5.1.112,doi:10.1073/pnas.0603522103,doi:10.1074/jbc.M102130200,doi:10.1093/pcp/pce112 IPT AT1G68460,AT3G63110,AT5G19040,AT3G23630,AT1G25410,AT3G19160,AT4G24650 iP-ribotide Metabolite Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) isopentenyl adenine ribotides chebi:71679 DAD1[AT2G44810] PlantCoding DAD1 fc00387 Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) Chloroplastic phospholipase A1 AT2G44810 phospholipids Metabolite Stress - Biotic Stress - Biotic Common membrane phospholipids, such as phosphatidylcholine (PC) and phosphatidylethanolamine (PE) chebi:16247 Growth Process Signalling - Growth Signalling - Growth Normal plant growth related to development, primary metabolism, and biomass. JASSY[AT1G70480] PlantCoding JASSY fc00190 chloroplast outer membrane protein, required for OPDA translocation from chloroplast to cytoplasm Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) OPDA exporting chloroplast membrane protein gmm:34.16,doi:10.1073/pnas.1900482116 AT1G70480 DZ-glucosides Metabolite Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) dihydrozeatin glucosides chebi:133475,metacyc:cpd-4615,chebi:72612,metacyc:cpd-4616,chebi:80499,kegg:c16448,metacyc:cpd-4617,chebi:133477,metacyc:cpd-4621,pubchem:25201421 iP-riboside Metabolite Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) N6-isopentenyladenosine chebi:60283 tZ-riboside Metabolite Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) 9-ribosyl-trans-zeatin; [6-((E)-4-hydroxy-3-methylbut-2-enylamino)-9-β-D-ribofuranosylpurine] chebi:71693 EIN3(like)|JAZ Complex Hormone - Ethylene (ET) Hormone - Ethylene (ET),Hormone - Jasmonate (JA) EIN3(like)[AT2G27050,AT3G20770] PlantCoding EIN3(like) fc00063 Ethylene insensitive 3 and Ethylene insensitive 3-like Hormone - Ethylene (ET) Hormone - Ethylene (ET) EIN3 and EIN3-like transcription factors gmm:27.3.19,kegg:k14514 EIN3(like) AT2G27050,AT3G20770 COI1|JA-Ile|SCF Complex Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) CI|VPg Complex Stress - Biotic Stress - Biotic,Stress - Biotic CI,VPg tZ-ribotide Metabolite Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) 9-ribosyl-trans-zeatin-5′-triphosphate chebi:71938 tZ-glucoside Metabolite Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) trans-zeatin glucosides chebi:80494,chebi:72609,chebi:38266,chebi:172726,kegg:c03423,kegg:c16443 p-Coumaric acid Metabolite Primary metabolism - Amino-acids Primary metabolism - Amino-acids,Hormone - Salicylic acid (SA) Hydroxycinnamic acid isonomer chebi:32374,pubchem:637542,metacyc:coumarate,kegg:C00811 Phenolics production Process Stress - Biotic Stress - Biotic Phenolic compounds (such as coumaric acid) production, leading towards alkaloids, and the destruction of pathogens/insects. iP-glucosides Metabolite http://www.olchemim.cz/Products.aspx?idc=1&idp=1; DOI:10.1016/j.trac.2008.11.010; DOI:10.3389/fpls.2016.01264 Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) isopentenyl adenine glucosides chebi:74321,metacyc:cpd-4602,chebi:72616,metacyc:cpd-4603,doi:10.1016/j.trac.2008.11.010,doi:10.3389/fpls.2016.01264,doi:10.1016/j.trac.2008.11.010 CYP735A1,A2[AT1G67110,AT5G38450] PlantCoding CYP735A1,A2 fc00052 Hormone - Cytokinins (CK) Hormone - Cytokinins (CK) cytochrome P450, family 735, subfamily A, polypeptide 1,2 ec:1.14.13.-,gmm:26.1 CYP735 AT5G38450,AT1G67110 miR168[AT4G19395,MIR168] PlantNonCoding miR168 fc00334 Encodes a microRNA that targets AGO1. MIR168a is highly expressed and predominantly produces a 21-nt miR168 species. By contrast, MIR168b is expressed at low levels and produces an equal amount of 21- and 22-nt miR168 species. Only the 21-nt miR168 is preferentially stabilized by AGO1. Regulation - Silencing Regulation - Silencing microRNA 168A mirbase:mi0000210,tair:locus:1009023317,pmid:20823831,doi:10.1038/emboj.2010.215 AT4G19395 MIR168 NPR1|NPR1 Complex Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) TRX-H[AT1G45145,AT5G42980] PlantCoding TRX-H fc00155 Only TRX3/5 are implicated in rx00096 (NPR complex monomerisation). Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) thioredoxin gmm:21.1 TRX-H AT5G42980,AT1G45145 EBF|SCF Complex Hormone - Ethylene (ET) Hormone - Ethylene (ET) Trichome-initiation Process Secondary metabolism - Terpenoids Secondary metabolism - Terpenoids Initiation of trichome growth. conceptual:process ARF[AT1G19850,AT2G33860,AT5G60450,AT5G62000] PlantCoding ARF fc00187 ARF3 is a target of the ta-siRNA tasiR-ARF. ARF4 appears to have redundant function with ETT(ARF3) in specifying abaxial cell identity. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Promotes flowering, stamen development, floral organ abscission and fruit dehiscence. Functions independently of ethylene and cytokinin response pathways. May act as a repressor of cell division and organ growth. Hormone - Auxins (AUX) Hormone - Auxins (AUX) auxin response transcription factor gmm:27.3.4 ARF AT1G19850,AT2G33860,AT5G60450,AT5G62000 TAS3[AT3G17185,AT5G49615] PlantNonCoding TAS3 fc00175 Encodes a trans-acting siRNA (tasi-RNA) that regulates the expression of auxin response factor genes (ARF2, ARF4, ETT). One of 3 genomic loci that encode the TAS3 siRNA. In contrast to the single mRNA binding family, TAS3 requires the guide mRNA miR390 bind the transcript at two sites. The transcript is then cleaved at the 3’ binding site only, by AGO7. As is the case for the TAS1, TAS2, and TAS3 families, RDR6 then synthesizes the dsRNA fragment which is further processed by DCL4. Regulation - Silencing Regulation - Silencing trans-acting siRNA3 TAS3 AT3G17185,AT5G49615 UPL5[AT4G12570] PlantCoding UPL5 fc00159 Regulates leaf senescence through ubiquitination and subsequent degradation of WRKY53. Degradation - Ubiquitination Degradation - Ubiquitination ubiquitin protein ligase, HECT E3 class gmm:29.5.11.4.1 HECT AT4G12570 AOX[AT1G32350,AT3G22370] PlantCoding AOX fc00023 Primary metabolism - Respiration Primary metabolism - Respiration Ubiquinol oxidase 3, mitochondrial AOX AT1G32350,AT3G22370 CAMTA3[AT2G22300,SOTUB04G020530.1.1] PlantCoding CAMTA3 fc00036 Transcription factor. Repressor of SA defence. Encodes a putative CAM binding transcription factor. Loss of function mutations show enhanced resistance to fungal and bacterial pathogens suggesting that CAMTA functions to suppress defense responses. Signalling - Calcium Signalling - Calcium calmodulin-binding transcription activator 3 gmm:17.5.3,gmm:27.3.39,kegg:k21596 CAMTA AT2G22300 SOTUB04G020530.1.1 SR1IP1[AT5G67385] PlantCoding SR1IP1 fc00152 Mediates cullin 3 (CAMTA3) based proteasome degradation. Phototropic-responsive NPH3-like protein. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Degradation - Ubiquitination Degradation - Ubiquitination SR1/CAMPTA3 interacting protein gmm:30.11,doi:10.1111/tpj.12473 NPH3 AT5G67385 APX[AT1G07890,AT3G09640,AT4G09010,AT4G32320,AT4G35000,AT4G35970] PlantCoding APX fc00025 Signalling - Reactive oxygen species (ROS) Signalling - Reactive oxygen species (ROS) ascorbate peroxidase 1,2,3,4,5,6 pmid:23412747,gmm:21.2.1,gmm:26.12 APX AT3G09640,AT4G35000,AT1G07890,AT4G35970,AT4G32320,AT4G09010 GPX[AT1G63460,AT2G25080,AT2G31570,AT2G43350,AT2G48150,AT3G63080,AT4G11600,AT4G31870] PlantCoding GPX fc00078 Signalling - Reactive oxygen species (ROS) Signalling - Reactive oxygen species (ROS) Glutathione peroxidase doi:10.1016/j.jplph.2014.12.014 GPX AT2G25080,AT2G31570,AT2G43350,AT2G48150,AT3G63080,AT4G11600,AT4G31870,AT1G63460 vsiRNA34327 ForeignNonCoding Regulation - Silencing Regulation - Silencing virus-derived small interfering RNA targeting GA1 doi:10.3389/fpls.2017.02192,pmid:29312421 vsiRNA12986 ForeignNonCoding vsiRNA12986 Regulation - Silencing Regulation - Silencing virus-derived small interfering RNA targeting GA20ox doi:10.3389/fpls.2017.02192,pmid:29312421 Waterlogging ForeignAbiotic Stress - Waterlogging Stress - Waterlogging O2-deficiency Process Primary metabolism - Respiration Primary metabolism - Respiration Insufficient availability of oxygen. phasiRNA931[PHASIRNA931] PlantNonCoding phasiRNA931 fc00181 Regulation - Silencing Regulation - Silencing phasiRNA targetting GA3ox doi:10.3389/fpls.2017.02192 phasiRNA931 PHASIRNA931 RISC - vsiRNA Complex Regulation - Silencing Regulation - Silencing RNA-induced silencing complex doi:10.1038/nrmicro1239 MYB33,44,65[AT3G11440,AT5G06100,AT5G67300,SOTUB06G030530.1.1] PlantCoding MYB33,44,65 fc00309 gibberellin induced TF Secondary metabolism - Anthocyanins Secondary metabolism - Anthocyanins MYB transcription factors 33,44,65 gmm:27.3.25 MYB AT3G11440,AT5G06100,AT5G67300 SOTUB06G030530.1.1 miR159AB[AT1G18075,AT1G73687] PlantNonCoding miR159AB fc00176 Encodes microRNA’s that target several MYB family members. miR159A and miR159B function redundantly. Plants that are doubly mutated for miR159AB have curled leaves and reduced stature. Regulation - Silencing Regulation - Silencing microRNA 159AB mirbase:mi0000189,mirbase:mi0000218,doi:10.1104/pp.110.160630,tair:locus:1009023075,tair:locus:1009023126 miR159 AT1G73687,AT1G18075 miR319a-3p[MIR319A-3P] PlantNonCoding miR319a-3p fc00179 Harbors general WRKY binding W-box regulatory element. In Arabidopsis, predominantly targets TCP transcription factor genes, and in contrast, statistical as well as experimentally established criteria have suggested that miR319 should be as efficient in targeting MYB33 and MYB65 as miR159. Regulation - Silencing Regulation - Silencing microRNA 319A doi:10.1016/j.devcel.2007.04.012,doi:10.3389/fpls.2017.02192,mirbase:mi0000544 miR319 MIR319A-3P D53[OS11G0104300] PlantCoding D53 fc00055 Substrate of the SCFD3 ubiquitination complex, Repressor of strigolactone (SL) signalling Hormone - Strigolactones (SL) Hormone - Strigolactones (SL) Protein DWARF 53 uniprotkb:q2rbp2 Class I Clp ATPase OS11G0104300 Cu2+ Metabolite Hormone - Ethylene (ET) Hormone - Ethylene (ET) Copper chebi:29036 HMA[AT1G63440,AT5G44790] PlantCoding HMA fc00082 HMA transporter Hormone - Ethylene (ET) Hormone - Ethylene (ET) copper-exporting ATPase ec:3.6.3.4,gmm:34.12 HMA AT5G44790,AT1G63440 CTS[AT4G39850] PlantCoding CTS fc00050 Encodes a peroxisomal protein of the ATP binding cassette (ABC) transporter class (PMP subfamily). Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) ATP-binding cassette D1 gmm:34.16 CTS AT4G39850 JAT2[AT2G39350] PlantCoding JAT2 fc00005 Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) ABC-2 type transporter family protein gmm:34.16,tair:locus:2039682,doi:10.3389/fpls.2019.00390 ABCG AT2G39350 MOS[AT1G80680,AT4G02150,AT5G05680] PlantCoding MOS fc00105 Involved in basal resistance against bacterial pathogens. Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) importin-alpha isoform (IMPA/MOS) gmm:29.3.1,doi:10.1016/j.cub.2005.05.022,doi:10.1016/j.tcb.2004.07.016 MOS AT4G02150,AT5G05680,AT1G80680 ETR[AT1G04310,AT1G66340,AT2G40940,AT3G04580,AT3G23150] PlantCoding ETR fc00075 ERS1, ERS2 have no receiver domain. ETR1, EIN4, ETR2 have receiver domain on the C terminus. Hormone - Ethylene (ET) Hormone - Ethylene (ET) ethylene receptor gmm:17.5.2,ec:2.7.13.-,kegg:ko04075,pmid:12045274 ETR AT1G04310,AT1G66340,AT2G40940,AT3G04580,AT3G23150 CTR|ETR Complex Hormone - Ethylene (ET) Hormone - Ethylene (ET) RTE1[AT2G26070] PlantCoding RTE1 fc00142 In Arabidopsis, it appears to be involved in the negative regulation of the response to ethylene, is localized to the Golgi and is a positive regulator of ETR1. Hormone - Ethylene (ET) Hormone - Ethylene (ET) protein REVERSION-TO-ETHYLENE SENSITIVITY-like protein (DUF778) RTE1 AT2G26070 EIN2[AT5G03280] PlantCoding EIN2 fc00062 EIN2 transporter. Involved in ethylene signal transduction. Acts downstream of CTR1. Hormone - Ethylene (ET) Hormone - Ethylene (ET) EIN2 transporter, NRAMP metal ion transporter family protein kegg:k14513,gmm:34.12;kegg:map04075 EIN2 AT5G03280 ETP|SCF Complex Hormone - Ethylene (ET) Hormone - Ethylene (ET) MPK4[AT4G01370] PlantCoding MPK4 fc00106 Encodes a nuclear and cytoplasmically localized MAP kinase involved in mediating responses to pathogens. Its substrates include MKS1 and probably MAP65-1. Signalling - MAP kinases (MAPKs) Signalling - MAP kinases (MAPKs) mitogen-activated protein (MAP) kinase 4 gmm:29.4,gmm:30.6 MAPK AT4G01370 VISO[unknown] PlantAbstract VISO fc00420 an unknown isomerase catalyzes all-trans-violaxanthin to 9′-cis-violaxanthin directly. Hormone - Abscisic acid (ABA)) Hormone - Abscisic acid (ABA) Violaxanthin isomerase doi:10.1111/j.1365-313X.2007.03094.x,doi:10.1111/jipb.12899 9-cis-Violaxanthin Metabolite Hormone - Abscisic acid (ABA) Hormone - Abscisic acid (ABA) 9-cis-Violaxanthin pubchem:586175,chebi:35305,kegg:c13433 Violaxanthin Metabolite Hormone - Abscisic acid (ABA) Hormone - Abscisic acid (ABA) Violaxanthin pubchem:10807,chebi:35288,kegg:c08614 SA low Condition Low SA concentration doi:10.3389/fpls.2014.00697,pmid:25538725 f(SA)=|SA|t MKK1[AT4G26070] PlantCoding MKK1 fc00250 Member of MAP kinase kinase. Likely functions in a stress-activated MAPK pathway. Can phosphorylate MPK4 in response to stress. Gets phosphorylated by MEKK1 (MAPKKK8) in response to wounding. Can directly interact with senescence-related WRKY53 transcription factor on the protein level and can bind to its promoter. MAPK/ERK kinase kinase 1; Involved in the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6) downstream of bacterial flagellin receptor FLS2. May be involved in the cold and salinity stress-mediated MAP kinase signaling cascade (MEKK1, MEK1/MKK2 and MPK4/MPK6). Activates downstream MKK2, MKK4 and MKK5. Signalling - MAP kinases (MAPKs) Signalling - MAP kinases (MAPKs) mitogen-activated protein (MAP) kinase/ ERK kinase 1 gmm:29.4.1,gmm:30.6 AT4G26070 MKD1[AT5G11850] PlantCoding MKD1 fc00186 Signalling - MAP kinases (MAPKs) Signalling - MAP kinases (MAPKs) Protein kinase superfamily protein gmm:29.4,gmm:30.6 AT5G11850 IAM Metabolite Hormone - Auxins (AUX) Hormone - Auxins (AUX) indole-3-acetamide chebi:16031,pubchem:397,metacyc:cpd-237 Trp Metabolite Hormone - Auxins (AUX) Hormone - Auxins (AUX) Tryptophan chebi:57912,pubchem:6305,metacyc:trp iaaM[unknown] PlantAbstract iaaM fc00253 Hormone - Auxins (AUX) Hormone - Auxins (AUX) unknown enzyme SARD1[AT1G73805] PlantCoding SARD1 fc00254 Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) Calmodulin binding protein-like protein gmm:30.3 AT1G73805 Thiohydroximate Metabolite Hormone - Auxins (AUX) Hormone - Auxins (AUX) Indolylmethylthiohydroximate chebi:80544,metacyc:CPD-1861,kegg:C16516 S-alkyl-thiohydroximate Metabolite Hormone - Auxins (AUX) Hormone - Auxins (AUX) S-(Indolylmethylthiohydroximoyl)-L-cysteine chebi:80546,pubchem:134820511,metacyc:cpd-7547 SUR1[AT2G20610] PlantCoding SUR1 fc00255 Confers auxin overproduction. Mutants have an over-proliferation of lateral roots. Encodes a C-S lyase involved in converting S-alkylthiohydroximate to thiohydroximate in glucosinolate biosynthesis. Hormone - Auxins (AUX) Hormone - Auxins (AUX) Tyrosine transaminase family protein metacyc:at2g20610,gmm:13.1.6.4.3 AT2G20610 OSCA1.3[AT1G11960] PlantCoding OSCA1.3 fc00398 Calcium channel that is phosphorylated by BIK1 in the presence of PAMPS and required for stomatal immunity. Stress - Drought Stress - Drought Calcium channel AT1G11960 5-phosphomevalonate Metabolite Secondary metabolism - Terpenoids Secondary metabolism - Terpenoids mevalonic acid-5-phosphate chebi:17436,pubchem:439400 MVA Metabolite Precursor of isoprenoids and cholesterol Secondary metabolism - Terpenoids Secondary metabolism - Terpenoids Mevalonic acid chebi:36464,pubchem:439230,metacyc:MEVALONATE,kegg:C00418 MVK[AT5G27450] PlantCoding MVK fc00256 Secondary metabolism - Terpenoids Secondary metabolism - Terpenoids mevalonate kinase metacyc:at5g27450 AT5G27450 TCP8[AT1G58100] PlantCoding TCP8 fc00258 Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) TCP family transcription factor gmm:27.3.29 AT1G58100 IAA Metabolite Hormone - Auxins (AUX) Hormone - Auxins (AUX) Indole-3-acetic acid chebi:30854,pubchem:801,metacyc:indole_acetate_auxin IAA-Ala Metabolite Hormone - Auxins (AUX) Hormone - Auxins (AUX) N-(indole-3-acetyl)-L-alanine chebi:71672,pubchem:644225,metacyc:indole-3-acetyl-ala IAR[AT1G51760,AT1G68100] PlantCoding IAR fc00227 Hormone - Auxins (AUX) Hormone - Auxins (AUX) IAA-alanine resistance protein gmm:17.2.1,gmm:34.12 AT1G51760,AT1G68100 IPA Metabolite Hormone - Auxins (AUX) Hormone - Auxins (AUX) Indole-3-pyruvate chebi:17640,pubchem:803,metacyc:indole_pyruvate TAA1[AT1G70560] PlantCoding TAA1 fc00260 Hormone - Auxins (AUX) Hormone - Auxins (AUX) tryptophan aminotransferase of Arabidopsis 1 metacyc:at1g70560,gmm:16.5.99.1 AT1G70560 BAK1|BRI1 Complex Hormone - Brassinosteroids (BS) Hormone - Brassinosteroids (BS) BRASSINOSTEROID-INSENSITIVE1 and BRI1-ASSOCIATED KINASE1(SERK3) BRI1,BAK1 BRI1[AT4G39400] PlantCoding BRI1 fc00321 Hormone - Brassinosteroids (BS) Hormone - Brassinosteroids (BS) Leucine-rich receptor-like protein kinase family protein AT4G39400 Brassinolide Metabolite Brassinolide is the most active brassinosteroid (BR), a class of polyhydroxylated steroidal phytohormones in plants. BRs regulate a wide range of physiological processes including plant growth, development and immunity. Hormone - Brassinosteroids (BS) Hormone - Brassinosteroids (BS) Brassinosteroid chebi:28277,pubchem:11007,metacyc:cpd-697 IAOx Metabolite Hormone - Auxins (AUX) Hormone - Auxins (AUX) (E)-(indol-3-yl)acetaldehyde oxime chebi:17545,pubchem:5371769,metacyc:indole-3-acetaldoxime CYP79B2[AT4G39950] PlantCoding CYP79B2 fc00261 Hormone - Auxins (AUX) Hormone - Auxins (AUX) cytochrome P450, family 79, subfamily B, polypeptide 2 metacyc:at4g39950,gmm:26.1 AT4G39950 IAOx N-oxide Metabolite Hormone - Auxins (AUX) Hormone - Auxins (AUX) 1-aci-nitro-2-(1H-indol-3-yl)ethane chebi:136445,pubchem:15663323 CYP83B1[AT4G31500] PlantCoding CYP83B1 fc00262 Hormone - Auxins (AUX) Hormone - Auxins (AUX) cytochrome P450, family 83, subfamily B, polypeptide 1 metacyc:at4g31500,gmm:26.1 AT4G31500 IAN Metabolite Hormone - Auxins (AUX) Hormone - Auxins (AUX) indole-3-acetonitrile chebi:17566,pubchem:351795,metacyc:indoleyl-cpd NIT1[AT3G44310] PlantCoding NIT1 fc00263 Hormone - Auxins (AUX) Hormone - Auxins (AUX) nitrilase 1 metacyc:at3g44310,gmm:16.5.1.3.3 AT3G44310 AMI1[AT1G08980] PlantCoding AMI1 fc00264 Hormone - Auxins (AUX) Hormone - Auxins (AUX) amidase 1 metacyc:at1g08980,gmm:29.3.3 AT1G08980 LECRK19[AT5G60300] PlantCoding LECRK19 fc00259 Signalling - Perception and resistance genes Signalling - Perception and resistance genes Concanavalin A-like lectin protein kinase family protein gmm:29.4,gmm:30.2.19 AT5G60300 SARD1|TCP8 Complex Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) TCP8[AT1G58100],SARD1[AT1G73805] TCP8|WRKY28 Complex Hormone - Salicylic acid (SA) Regulation - Transcription & Translation,Hormone - Salicylic acid (SA) TCP8[AT1G58100],WRKY28[AT4G18170] NAC019|TCP8 Complex Hormone - Abscisic acid (ABA) Hormone - Abscisic acid (ABA),Hormone - Salicylic acid (SA) TCP8[AT1G58100],NAC019[AT1G52890] FKBP65[AT5G48570] PlantCoding FKBP65 fc00266 Signalling - Heat-shock proteins (HSPs) Signalling - Heat-shock proteins (HSPs) FKBP-type peptidyl-prolyl cis-trans isomerase family protein gmm:31.3.1 AT5G48570 IAA-Leu Metabolite Hormone - Auxins (AUX) Hormone - Auxins (AUX) N-(indole-3-acetyl)-L-leucine chebi:71675,pubchem:688142,metacyc:indole-3-acetyl-leu ILR1[AT3G02875] PlantCoding ILR1 fc00267 Hormone - Auxins (AUX) Hormone - Auxins (AUX) Peptidase M20/M25/M40 family protein gmm:17.2.1 AT3G02875 UTR1[AT2G02810] PlantCoding UTR1 fc00268 Regulation - Transport Regulation - Transport UDP-galactose transporter 1 gmm:34.11 AT2G02810 SIK1[AT1G69220] PlantCoding SIK1 fc00269 Signalling - Growth Signalling - Growth Protein kinase superfamily protein gmm:29.4.1 AT1G69220 RDR1,6[AT1G14790,AT3G49500] PlantCoding RDR1,6 fc00337 RDRs are a family of proteins that produce double-stranded small RNA (sRNA) precursors by synthesizing the complementary strand of a single-stranded RNA template. Regulation - Silencing Regulation - Silencing RNA-dependent RNA polymerases gmm:27.2,doi:10.1105/tpc.109.073056,doi:10.1073/pnas.0904086107,tair:locus:2006822,tair:locus:2114633 AT1G14790,AT3G49500 MeIAA Metabolite Hormone - Auxins (AUX) Hormone - Auxins (AUX) methyl (indol-3-yl)acetate pubchem:74706,metacyc:cpd-10546,chebi:72782 IAMT1[AT5G55250] PlantCoding IAMT1 fc00271 Encodes an enzyme which specifically converts IAA to its methyl ester form MelIAA. Hormone - Auxins (AUX) Hormone - Auxins (AUX) IAA carboxylmethyltransferase 1 metacyc:at5g55250,gmm:17.2.1 AT5G55250 BGLU30[AT3G60140] PlantCoding BGLU30 fc00272 Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) Glycosyl hydrolase superfamily protein gmm:26.3 AT3G60140 CYP81F4[AT4G37410] PlantCoding CYP81F4 fc00273 Secondary metabolism - Alkaloids Secondary metabolism - Alkaloids cytochrome P450, family 81, subfamily F, polypeptide 4 gmm:26.1 AT4G37410 DR4[AT1G73330] PlantCoding DR4 fc00274 Hormone - Abscisic acid (ABA) Hormone - Abscisic acid (ABA) drought-repressed 4 gmm:20.1.7.6 AT1G73330 ERF016[AT5G21960] PlantCoding ERF016 fc00275 Hormone - Ethylene (ET) Hormone - Ethylene (ET) ethylene response factor 16 gmm:17.5.2,gmm:27.3.3 AT5G21960 eATP Metabolite Extracellular ATP (eATP) is now recognized as an important signaling agent in plant growth and defense response to environmental stimuli. Signalling - Other Signalling - Other extracellular ATP chebi:15422,pubchem:5957,doi:10.4161/psb.19857,pmid:22516815 IAA-Glu Metabolite Hormone - Auxins (AUX) Hormone - Auxins (AUX) 1-O-(indol-3-ylacetyl)-β-D-glucose chebi:17990,pubchem:440255,metacyc:cpd-1102 UGT84B1[AT2G23260] PlantCoding UGT84B1 fc00278 Hormone - Auxins (AUX) Hormone - Auxins (AUX) UDP-glucosyl transferase 84B1 gmm:26.2 AT2G23260 IAA-Asp Metabolite Hormone - Auxins (AUX) Hormone - Auxins (AUX) (indol-3-yl)acetyl-L-aspartate chebi:133482,pubchem:6921620,metacyc:indole-3-acetyl-asp DOPAL Metabolite Primary metabolism - Amino-acids Primary metabolism - Amino-acids 3,4-dihydroxyphenylacetaldehyde chebi:27978,pubchem:119219,metacyc:34-dihydroxyphenylacetaldehyde PAA Metabolite Primary metabolism - Amino-acids Primary metabolism - Amino-acids Phenylacetaldehyde chebi:16424,pubchem:998,metacyc:phenylacetaldehyde L-Dopa Metabolite Primary metabolism - Amino-acids Primary metabolism - Amino-acids 3,4-dihydroxy-L-phenylalanine chebi:57504,pubchem:6971033,metacyc:l-dihydroxy-phenylalanine ELI5[AT2G20340] PlantCoding ELI5 fc00281 Primary metabolism - Amino-acids Primary metabolism - Amino-acids Pyridoxal phosphate (PLP)-dependent transferases superfamily protein gmm:16.4.1 AT2G20340 TIR1[AT3G62980] PlantCoding TIR1 fc00283 Hormone - Auxins (AUX) Hormone - Auxins (AUX) F-box/RNI-like superfamily protein gmm:17.2.2 AT3G62980 GH3.7[AT1G23160] PlantCoding GH3.7 fc00280 Hormone - Auxins (AUX) Hormone - Auxins (AUX) auxin-responsive GH3 family protein gmm:17.2.3 AT1G23160 HSP18.1-CI[AT5G59720] PlantCoding HSP18.1-CI fc00391 Signalling - Heat-shock proteins (HSPs) Signalling - Heat-shock proteins (HSPs) small heat shock protein cytoplasmic/nuclear-localized AT5G59720 SAUR41[AT1G16510] PlantCoding SAUR41 fc00284 Hormone - Auxins (AUX) Hormone - Auxins (AUX) SAUR-like auxin-responsive protein family gmm:17.2.3 AT1G16510 PP2C[AT3G11410,SOLTU.DM.03G012480.1,SOLTU.DM.06G031720.1,SOTUB03G021270.1.1,SOTUB06G032210.1.1] PlantCoding PP2C fc00286 Negative regulator of ABA signalling. Expressed in seeds during germination. mRNA up-regulated by drought and ABA. Stress - Waterlogging Stress - Waterlogging,Signalling - MAP kinases (MAPKs) protein phosphatase 2C gmm:17.1.2,gmm:29.4 AT3G11410 SOLTU.DM.03G012480.1,SOLTU.DM.06G031720.1,SOTUB03G021270.1.1,SOTUB06G032210.1.1 GBF4[AT1G03970] PlantCoding GBF4 fc00287 Signalling - MAP kinases (MAPKs) Signalling - MAP kinases (MAPKs) G-box binding factor 4 gmm:27.3.35 AT1G03970 BRAHMA[AT2G46020] PlantCoding BRAHMA fc00341 Encodes a SWI/SNF chromatin remodeling ATPase Stress - Heat Stress - Heat transcription regulatory protein SNF2 gmm:27.3.44 AT2G46020 GER3|VPg Complex GER3[AT5G20630],VPg GER3[AT5G20630] PlantCoding GER3 fc00372 germin 3 AT5G20630 bZIP21[AT1G08320] PlantCoding bZIP21 fc00288 Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) bZIP transcription factor family protein gmm:27.3.35 AT1G08320 HSP26.5-MII[AT1G52560] PlantCoding HSP26.5-MII fc00392 Signalling - Heat-shock proteins (HSPs) Signalling - Heat-shock proteins (HSPs) small heat shock protein mitochondrial-localized AT1G52560 Stomatal closure Process Stress - Drought Hormone - Abscisic acid (ABA),Stress - Drought Phenotype response to water deficit RD29[AT5G52300,AT5G52310,SOTUB03G014340.1.1] PlantCoding RD29 fc00192 Encodes a protein that is induced in expression in response to water deprivation such as cold, high-salt, and desiccation. The response appears to be via abscisic acid. Stress - Drought Stress - Heat,Hormone - Abscisic acid (ABA),Stress - Drought,Stress - Waterlogging Responsive to Desiccation 29 gmm:20.2.2 AT5G52300,AT5G52310 SOTUB03G014340.1.1 CAU1[AT4G31120] PlantCoding CAU1 fc00342 Encodes a histone methylase, functions as an upstream suppressor of CAS, and via this interaction serves as an essential player in the [Ca2+]o-mediated stomatal closure and drought tolerance. Hormone - Abscisic acid (ABA) Hormone - Abscisic acid (ABA) Calcium Underaccumulation 1 gmm:25,doi:10.1105/tpc.113.113886,tair:locus:2126276 AT4G31120 P5CS1[AT2G39800] PlantCoding P5CS1 fc00399 P5CS1 appears to be involved in salt stress responses related to proline accumulation, including protection from reactive oxidative species. Primary metabolism - Amino-acids Hormone - Abscisic acid (ABA),Primary metabolism - Amino-acids delta1-pyrroline-5-carboxylate synthase 1 AT2G39800 BSK[AT1G01740,AT1G50990,AT1G63500,AT2G17090,AT3G09240,AT3G54030,AT4G00710,AT4G35230,AT5G01060,AT5G41260,AT5G46570,AT5G59010] PlantCoding BSK fc00290 Hormone - Brassinosteroids (BS) Hormone - Brassinosteroids (BS) BR-signaling kinase kegg:k14500,ec:2.7.11.1,gmm:29.4.1.52,doi:10.1126/science.1156973,pmid:18653891 AT1G01740,AT1G50990,AT1G63500,AT2G17090,AT3G09240,AT3G54030,AT4G00710,AT4G35230,AT5G01060,AT5G41260,AT5G46570,AT5G59010 BSU1[AT1G03445] PlantCoding BSU1 fc00291 Hormone - Brassinosteroids (BS) Hormone - Brassinosteroids (BS) Serine/threonine protein phosphatase family protein kegg:k14501,gmm:17.3.2.1 AT1G03445 BZR2[AT1G19350] PlantCoding BZR2 fc00292 Hormone - Brassinosteroids (BS) Hormone - Brassinosteroids (BS) Brassinosteroid signaling positive regulator (BZR1) family protein gmm:17.3.2.2 AT1G19350 XTH[AT5G57560,PGSC0003DMG402010918] PlantCoding XTH fc00293 Hormone - Brassinosteroids (BS) Signalling - Calcium,Hormone - Brassinosteroids (BS) xyloglucan endotransglucosylase gmm:10.6.2,gmm:50.2.4 AT5G57560 PGSC0003DMG402010918 CYCD3-3[AT3G50070] PlantCoding CYCD3-3 fc00294 Encode CYCD3;3, a CYCD3 D-type cyclin. Important for determining cell number in developing lateral organs. Mediating cytokinin effects in apical growth and development. Hormone - Brassinosteroids (BS) Hormone - Brassinosteroids (BS) CYCLIN D3;3 gmm:31.3 AT3G50070 MKK4,5[AT1G51660,AT3G21220] PlantCoding MKK4,5 fc00295 Hormone - Ethylene (ET) Hormone - Ethylene (ET),Signalling - MAP kinases (MAPKs) Mitogen-Activated Protein (MAP) kinase kinase 4, 5 doi:10.1038/415977a,gmm:30.6 AT1G51660,AT3G21220 NPR1|WRKY18 Complex Hormone - Salicylic acid (SA) Regulation - Transcription & Translation,Hormone - Salicylic acid (SA) NPR1[AT1G64280],WRKY18[AT4G31800] CDK|NPR1 Complex Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) NPR1[AT1G64280],CDKE-1[AT5G63610] CDK[AT5G63610] PlantCoding CDK fc00297 Regulation - Transcription & Translation Regulation - Transcription & Translation cyclin-dependent kinase E-1 gmm:29.4 AT5G63610 CDK|WRKY6,18 Complex Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) CDKE-1[AT5G63610],WRKY18[AT4G31800] CDK|TGA Complex Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) CDKE-1[AT5G63610],TGA2,5,6[AT3G12250,AT5G06950,AT5G06960] PEPR[AT1G17750,AT1G73080] PlantCoding PEPR fc00298 Hormone - Peptides Hormone - Peptides PEP receptor gmm:30.2.11 AT1G73080,AT1G17750 TCP8,14,15[AT1G58100,AT1G69690,AT3G47620] PlantCoding TCP8,14,15 fc00332 Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) TCP family transcription factor gmm:27.3.29,doi:10.3389/fpls.2018.01153 AT1G58100,AT1G69690,AT3G47620 PEPR1|PEP1 Complex Hormone - Peptides Hormone - Peptides PEP1[AT5G64900],PEPR1[AT1G73080] PEP[AT2G22000,AT5G09976,AT5G09978,AT5G09980,AT5G09990,AT5G64890,AT5G64900,AT5G64905] PlantCoding PEP fc00299 Hormone - Peptides Hormone - Peptides Precursos of elicitor peptide gmm:20.1 AT5G64900,AT5G64890,AT5G64905,AT5G09980,AT5G09990,AT2G22000,AT5G09978,AT5G09976 BIK1|PEPR1|PEP1 Complex Signalling - Perception and resistance genes Signalling - Perception and resistance genes BIK1[AT2G39660],PEPR1|pep1 PA[AT2G22250] PlantCoding PA fc00121 Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) aspartate aminotransferase gmm:13.1.1.2.1 PA AT2G22250 ADT[AT1G08250,AT1G11790,AT2G27820,AT3G07630,AT3G44720,AT5G22630] PlantCoding ADT fc00016 Encodes plastid-localized arogenate dehydratase involved in phenylalanine biosynthesis. 10.1074/jbc.M702662200: Three of the resulting recombinant proteins, encoded by ADT1 (At1g11790), ADT2 (At3g07630), and ADT6 (At1g08250), more efficiently utilized arogenate than prephenate, whereas the remaining three, ADT3 (At2g27820), ADT4 (At3g44720), and ADT5 (At5g22630) essentially only employed arogenate. Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) arogenate dehydratase 1,2,3,4,5,6 gmm:13.1.6.3.1,doi:10.1074/jbc.M702662200 ADT AT1G11790,AT1G08250,AT3G44720,AT2G27820,AT3G07630,AT5G22630 CYP73A5[AT2G30490] PlantCoding CYP73A5 fc00329 Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) cinnamate-4-hydroxylase AT2G30490 PABP2|VPg Complex Regulation - Transcription & Translation Regulation - Transcription & Translation,Stress - Biotic PAB2[AT4G34110],VPg PAB2[AT4G34110] PlantCoding PAB2 fc00345 Regulation - Transcription & Translation Regulation - Transcription & Translation poly(A) binding protein 2 AT4G34110 viral dsRNA ForeignCoding Sources of viral dsRNA for generation of visRNA: (1) In positive strand (+) RNA viruses, the genome can be directly translated into replication proteins which associate with host proteins and viral RNA to form membranous structures where the negative (−) strands are synthesized, and double-stranded replication intermediates are formed, (2) In negative strand (−) RNA viruses, transcription (relying on viral RDR) leads to the production of messenger RNA (mRNA) which can form dsRNA by pairing with the genomic RNA, (3) In negative strand (−) RNA viruses, genomic RNA replication that leads to the formation of antigenome, complementary to the genomic RNA, can base-pair with genomic RNA, serving as the source of dsRNAs (4) In DNA viruses, overlapping transcription and transcripts with self-complementary regions are sources of dsRNA, (5) Aberrant RNAs produced due to cleavage by certain vsiRNAs, are acted upon by RDRPs1/6 to produce long dsRNAs. Regulation - Silencing Regulation - Silencing viral double stranded RNA (siRNAs precursor) doi:10.1080/07388551.2019.1597830 DCL2,4[AT3G03300,AT5G20320] PlantCoding DCL2,4 fc00335 In Arabidopsis, DCL2 and DCL4 process double-stranded RNA into 22 and 21 nucleotide small interfering (si)RNAs, respectively, and have overlapping functions with regards to virus and transgene silencing. DCL2 and DCL4 functions are mostly redundant. Regulation - Silencing Regulation - Silencing Dicer-like proteins gmm:27.1.20,doi:10.1111/tpj.12720 AT3G03300,AT5G20320 vsiRNA ForeignNonCoding siRNAs are derived from dsRNA precursors in a DCL dependent manner. During virus infection, endogenous as well as virus-derived small RNAs enable the plants to devise an appropriate strategy to counter the attack. Regulation - Silencing Regulation - Silencing viral-derived small interfering RNAs doi:10.1080/07388551.2019.1597830 SAH Metabolite Hormone - Ethylene (ET) Hormone - Ethylene (ET) S-adenosyl-l-homocysteine kegg:c00021,chebi:16680,aracyc:adenosyl-homo-cys me-vsiRNA ForeignNonCoding sRNA duplexes formed during RNA silencing are protected from degradation through 2′–O-methylation of their 3′ ends by HEN1. Regulation - Silencing Regulation - Silencing methylated viral-derived small interfering RNAs doi:10.1080/07388551.2019.1597830 PABP4|VPg Complex Regulation - Transcription & Translation Regulation - Transcription & Translation,Stress - Biotic PAB4[AT2G23350],VPg PAB4[AT2G23350] PlantCoding PAB4 fc00346 Regulation - Transcription & Translation Regulation - Transcription & Translation poly(A) binding protein 4 AT2G23350 HC-Pro|vsiRNA Complex Regulation - Silencing Regulation - Silencing In viral suppression of RNA-Silencing, Hc-Pro binds to vsiRNAs. L-homo-cys Metabolite Hormone - Ethylene (ET) Hormone - Ethylene (ET) L-homocysteine kegg:c00155,chebi:17588,aracyc:homo-cys MS[AT3G03780,AT5G17920] PlantCoding MS fc00336 Encodes a cytosolic methionine synthase, involved in methionine regeneration via the activated methyl cycle (or SAM cycle). Hormone - Ethylene (ET) Hormone - Ethylene (ET) Methionine Synthase gmm:13.1.3.4.3,doi:10.1016/S0960-9822(03)00293-8,tair:locus:2170318,tair:locus:2079434 AT3G03780,AT5G17920 ET|ETR Complex Hormone - Ethylene (ET) Hormone - Ethylene (ET) PABP8|VPg Complex Regulation - Transcription & Translation Regulation - Transcription & Translation,Stress - Biotic PAB8[AT1G49760],VPg PAB8[AT1G49760] PlantCoding PAB8 fc00347 Regulation - Transcription & Translation Regulation - Transcription & Translation poly(A) binding protein 8 AT1G49760 PA Metabolite Stress - Biotic Stress - Biotic Phosphatidic Acid chebi:16337,metacyc:l-phosphatidate,kegg:c00416 PLDALPHA1[AT3G15730] PlantCoding PLDALPHA1 fc00348 Hormone - Abscisic acid (ABA) Hormone - Abscisic acid (ABA) phospholipase D alpha 1 AT3G15730 GSNO[AT5G43940] PlantCoding GSNO fc00080 Gene expression is reduced by wounding and induced by salicylic acid. Required for the acclimation of plants to high temperature, and for fertility. Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) GroES-like zinc-binding dehydrogenase family protein gmm:5.3,gmm:26.11.1 GSNO AT5G43940 Glu Metabolite Primary metabolism - Amino-acids Primary metabolism - Amino-acids Glutamate chebi:29985,pubchem:5460299,metacyc:glt PBS3[AT5G13320] PlantCoding PBS3 fc00137 Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) Auxin-responsive GH3 family protein gmm:17.2.3 AT5G13320 6K2|VPg Complex Stress - Biotic Stress - Biotic,Stress - Biotic 6K2,VPg 6K2 ForeignCoding Stress - Biotic Stress - Biotic small peptide of unknown functions doi:10.1016/j.coviro.2012.09.004 virus RISC - miR390 Complex Regulation - Silencing Regulation - Silencing AGO1[AT1G48410],MIR390[AT2G38325,AT5G58465] AGO7[AT1G69440] PlantCoding AGO7 fc00350 Regulation - Silencing Regulation - Silencing Argonaute family protein AT1G69440 PORB|VPg Complex Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis,Stress - Biotic PORB[AT4G27440],VPg PORB[AT4G27440] PlantCoding PORB fc00351 Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis,Hormone - Ethylene (ET) protochlorophyllide oxidoreductase B AT4G27440 PORA|VPg Complex Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis,Stress - Biotic PORA[AT5G54190],VPg PORA[AT5G54190] PlantCoding PORA fc00352 Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis,Hormone - Ethylene (ET) protochlorophyllide oxidoreductase A AT5G54190 FBA8|VPg Complex Primary metabolism - Carbohydrates Primary metabolism - Carbohydrates,Stress - Biotic FBA8[AT3G52930],VPg FBA8[AT3G52930] PlantCoding FBA8 fc00353 Primary metabolism - Carbohydrates Primary metabolism - Carbohydrates Aldolase superfamily protein AT3G52930 GSTF9|VPg Complex GSTF9[AT2G30860],VPg GSTF9[AT2G30860] PlantCoding GSTF9 fc00354 glutathione S-transferase PHI 9 AT2G30860 HUP54|VPg Complex Stress - Waterlogging Stress - Waterlogging,Stress - Biotic [ORF]F27G19.50[AT4G27450],VPg HUP54[AT4G27450] PlantCoding HUP54 fc00355 Stress - Waterlogging Stress - Waterlogging aluminum induced protein with YGL and LRDR motifs AT4G27450 EDS5[AT4G39030] PlantCoding EDS5 fc00061 Exports SA to cytosol. Essential component of salicylic acid-dependent signaling for disease resistance. Member of the MATE-transporter family. Expression induced by salicylic acid. Mutants are salicylic acid-deficient. Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) MATE efflux family protein doi:10.1111/nph.13286,gmm:20.1 EDS5 AT4G39030 VDAC2|VPg Complex Regulation - Transport Regulation - Transport,Stress - Biotic VDAC2[AT5G67500],VPg VDAC2[AT5G67500] PlantCoding VDAC2 fc00356 Regulation - Transport Regulation - Transport voltage dependent anion channel 2 AT5G67500 PSBR|VPg Complex Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis,Stress - Biotic PSBR[AT1G79040],VPg PSBR[AT1G79040] PlantCoding PSBR fc00357 Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis photosystem II subunit R AT1G79040 LOX2|VPg Complex Hormone - Jasmonate (JA) Hormone - Jasmonate (JA),Stress - Biotic LOX[AT1G17420,AT1G55020,AT1G67560,AT1G72520,AT3G22400,AT3G45140,SOTUB03G034620.1.1],VPg P1|VPg Complex Stress - Biotic Stress - Biotic,Stress - Biotic P1,VPg P1 ForeignCoding Stress - Biotic Stress - Biotic serine protease doi:10.1016/j.coviro.2012.09.004 virus JAZ|MYC Complex Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) MSL[AT1G53470,AT1G58200,AT1G78610,AT2G17000,AT2G17010,AT3G14810,AT4G00290,AT5G10490,AT5G12080,AT5G19520] PlantCoding MSL fc00388 Stress - Waterlogging Stress - Waterlogging Mechanosensitive channel of Small conductance-Like AT4G00290,AT5G10490,AT1G58200,AT1G53470,AT3G14810,AT1G78610,AT2G17000,AT2G17010,AT5G19520,AT5G12080 NIa-Pro|VPg Complex Stress - Biotic Stress - Biotic,Stress - Biotic NIa-Pro,VPg NIa-Pro ForeignCoding Stress - Biotic Stress - Biotic protease doi:10.1016/j.coviro.2012.09.004 virus NIb|VPg Complex Stress - Biotic Stress - Biotic,Stress - Biotic NIb,VPg NIb ForeignCoding Stress - Biotic Stress - Biotic RNA-dependent RNA polymerase doi:10.1016/j.coviro.2012.09.004 virus CP|VPg Complex Stress - Biotic Stress - Biotic,Stress - Biotic CP,VPg BAS1|VPg Complex Signalling - Reactive oxygen species (ROS) Signalling - Reactive oxygen species (ROS),Stress - Biotic BAS1[AT3G11630],VPg BAS1[AT3G11630] PlantCoding BAS1 fc00373 Signalling - Reactive oxygen species (ROS) Signalling - Reactive oxygen species (ROS) Thioredoxin superfamily protein AT3G11630 RBCL|VPg Complex Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis,Stress - Biotic RBC[AT1G67090,AT5G38430,ATCG00490],VPg PSBP1|VPg Complex Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis,Stress - Biotic PSBP1[AT1G06680],VPg PSBP1[AT1G06680] PlantCoding PSBP1 fc00374 Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis photosystem II subunit P-1 AT1G06680 RCA|VPg Complex Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis,Stress - Biotic RCA[AT2G39730],VPg RCA[AT2G39730] PlantCoding RCA fc00375 Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis,Hormone - Jasmonate (JA),Signalling - Senescence rubisco activase AT2G39730 MED37E|VPg Complex Signalling - Heat-shock proteins (HSPs) Signalling - Heat-shock proteins (HSPs),Stress - Biotic MED37E[AT5G02500],VPg MED37E[AT5G02500] PlantCoding MED37E fc00376 Signalling - Heat-shock proteins (HSPs) Signalling - Heat-shock proteins (HSPs) heat shock cognate protein 70-1 AT5G02500 IPP2|VPg Complex Secondary metabolism - Terpenoids Secondary metabolism - Terpenoids,Stress - Biotic IPP2[AT3G02780],VPg IPP2[AT3G02780] PlantCoding IPP2 fc00377 Secondary metabolism - Terpenoids Secondary metabolism - Terpenoids isopentenyl pyrophosphate:dimethylallyl pyrophosphate isomerase 2 AT3G02780 ABCF1|VPg Complex Regulation - Transcription & Translation Regulation - Transcription & Translation,Stress - Biotic ABCF1[AT5G60790],VPg ABCF1[AT5G60790] PlantCoding ABCF1 fc00378 Regulation - Transcription & Translation Regulation - Transcription & Translation ABC transporter family protein AT5G60790 CLPR3|VPg Complex CLPR3[AT1G09130],VPg CLPR3[AT1G09130] PlantCoding CLPR3 fc00379 ATP-dependent caseinolytic (Clp) protease/crotonase family protein AT1G09130 MES10[AT3G50440] PlantCoding MES10 fc00401 Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) methylesterase AT3G50440 ACT[AT5G61160] PlantCoding ACT fc00380 Secondary metabolism - Anthocyanins Secondary metabolism - Anthocyanins anthocyanin 5-aromatic acyltransferase 1 AT5G61160 PSBB|VPg Complex Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis,Stress - Biotic psbB[ATCG00680],VPg psbB[ATCG00680] PlantCoding psbB fc00381 Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis photosystem II reaction center protein B ATCG00680 BCCP1|VPg Complex Primary metabolism - Lipids Primary metabolism - Lipids,Stress - Biotic BCCP1[AT5G16390],VPg BCCP1[AT5G16390] PlantCoding BCCP1 fc00382 Primary metabolism - Lipids Primary metabolism - Lipids chloroplastic acetylcoenzyme A carboxylase 1 AT5G16390 GRF6|VPg Complex Signalling - Reactive oxygen species (ROS) Signalling - Reactive oxygen species (ROS),Stress - Biotic GRF6[AT5G10450],VPg GRF6[AT5G10450] PlantCoding GRF6 fc00383 Signalling - Reactive oxygen species (ROS) Signalling - Reactive oxygen species (ROS) G-box regulating factor 6 AT5G10450 CAC2|VPg Complex Primary metabolism - Carbohydrates Primary metabolism - Carbohydrates,Stress - Biotic CAC2[AT5G35360],VPg CAC2[AT5G35360] PlantCoding CAC2 fc00384 Primary metabolism - Carbohydrates Primary metabolism - Carbohydrates,Primary metabolism - Lipids acetyl Co-enzyme a carboxylase biotin carboxylase subunit AT5G35360 GSTF2|VPg Complex GST[AT1G02920,AT1G02930,AT1G17170,AT2G02930,AT2G47730,AT4G02520],VPg MPPBETA|VPg Complex MPPBETA[AT3G02090],VPg MPPBETA[AT3G02090] PlantCoding MPPBETA fc00385 Insulinase (Peptidase family M16) protein AT3G02090 ATPC1|VPg Complex Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis,Stress - Biotic ATPC1[AT4G04640],VPg ATPC1[AT4G04640] PlantCoding ATPC1 fc00386 Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis ATPase%2C F1 complex%2C gamma subunit protein AT4G04640 MYC3[AT5G46760] PlantCoding MYC3 fc00403 Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) Transcription factor MYC3 AT5G46760 MYC3|NPR1 Complex Hormone - Jasmonate (JA) Hormone - Jasmonate (JA),Hormone - Salicylic acid (SA) MYC3[AT5G46760],NPR1[AT1G64280] MYC4|NPR1 Complex Hormone - Jasmonate (JA) Hormone - Jasmonate (JA),Hormone - Salicylic acid (SA) MYC4[AT4G17880],NPR1[AT1G64280] MYC4[AT4G17880] PlantCoding MYC4 fc00402 Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) Transcription factor MYC4 AT4G17880 CPI8[SOTUB03G015970.1.1] PlantCoding CPI8 fc00404 Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) Cysteine protease inhibitor 8 SOTUB03G015970.1.1 MC[SOTUB06G030610.1.1] PlantCoding MC fc00405 Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) Cysteine proteinase inhibitor SOTUB06G030610.1.1 ADH1[AT1G77120] PlantCoding ADH1 fc00406 alcohol dehydrogenase 1 AT1G77120 ERF-VII[AT1G53910,AT1G72360,AT2G47520,AT3G14230,AT3G16770] PlantCoding ERF-VII fc00400 Hormone - Ethylene (ET) Hormone - Ethylene (ET) Group VII ethylene response factors AT1G72360,AT2G47520,AT1G53910,AT3G14230,AT3G16770 CNGC2[AT5G15410] PlantCoding CNGC2 fc00407 Cyclic nucleotide-regulated ion channel family protein AT5G15410 GAI|GI Complex GI[AT1G22770],DELLA[AT1G14920,AT1G66350,AT2G01570,AT3G03450,AT5G17490] GI[AT1G22770] PlantCoding GI fc00408 gigantea protein (GI) AT1G22770 GI|PIF4 Complex GI[AT1G22770],PIF4[AT2G43010] PIF4[AT2G43010] PlantCoding PIF4 fc00409 phytochrome interacting factor 4 AT2G43010 P5C Metabolite Primary metabolism - Amino-acids,Stress - Drought 1-Pyrroline-5-carboxylate chebi:17388,pubchem:11966181,metacyc:l-delta1-pyrroline_5-carboxylate Proline accumulation Process Primary metabolism - Amino-acids Stress - Drought,Primary metabolism - Amino-acids Phenotype response to water deficit PROC1[AT5G14800] PlantCoding PROC1 fc00411 pyrroline-5- carboxylate (P5C) reductase AT5G14800 MYB2[AT2G47190] PlantCoding MYB2 fc00412 Hormone - Abscisic acid (ABA),Hormone - Cytokinins (CK) myb domain protein 2 kegg:k09422 AT2G47190 ATAF1[AT1G01720] PlantCoding ATAF1 fc00413 Hormone - Abscisic acid (ABA) Hormone - Abscisic acid (ABA) NAC (No Apical Meristem) domain transcriptional regulator superfamily protein AT1G01720 PTP1a[SOTUB06G024510.1.1] PlantCoding PTP1a fc00419 Stress - Biotic Stress - Biotic Protein tyrosine phosphatase non-receptor type 6 SOTUB06G024510.1.1 MKK1[SOTUB12G010200.1.1] PlantCoding MKK1 fc00417 Signalling - MAP kinases (MAPKs) Signalling - MAP kinases (MAPKs) Protein kinase SOTUB12G010200.1.1 NAC92[AT5G39610] PlantCoding NAC92 fc00418 Signalling - Senescence Signalling - Senescence NAC domain containing protein 6 AT5G39610 EIN3|NPR1 Complex NPR1[AT1G64280],EIN3(like)[AT2G27050,AT3G20770] HY5[AT5G11260] PlantCoding HY5 fc00421 Hormone - Abscisic acid (ABA),Regulation - Transcription & Translation Basic-leucine zipper (bZIP) transcription factor family protein AT5G11260 InsP5 Metabolite Signalling - Phospho-inosytol-phosphate (PIP) Signalling - Phospho-inosytol-phosphate (PIP) soluble inositol pentakisphosphate pubchem:482,kegg:c15991,chebi:57733 ITPK1[AT5G16760] PlantCoding ITPK1 fc00427 Signalling - Phospho-inosytol-phosphate (PIP) Signalling - Phospho-inosytol-phosphate (PIP) Inositol 1%2C3%2C4-trisphosphate 5/6-kinase family protein metacyc:at5g16760,kegg:k00913 AT5G16760 InsP4 Metabolite Signalling - Phospho-inosytol-phosphate (PIP) Signalling - Phospho-inosytol-phosphate (PIP) InsP6 Metabolite Signalling - Phospho-inosytol-phosphate (PIP) Signalling - Phospho-inosytol-phosphate (PIP) soluble inositol pentakisphosphate 6 chebi:58130,pubchem:21584050,kegg:75678 IPK1[AT5G42810] PlantCoding IPK1 fc00428 Signalling - Phospho-inosytol-phosphate (PIP) Signalling - Phospho-inosytol-phosphate (PIP) inositol-pentakisphosphate 2-kinase 1 pubchem:834292,metacyc:at5g42810,kegg:k19786 AT5G42810 InsP7 Metabolite Signalling - Phospho-inosytol-phosphate (PIP) Signalling - Phospho-inosytol-phosphate (PIP) soluble inositol pentakisphosphate chebi:30164,kegg:c11526 CDK|RAP2-6 Complex CDK[AT5G63610],RAP2-6[AT1G43160] RAP2-6[AT1G43160] PlantCoding RAP2-6 fc00429 related to AP2 6 AT1G43160 RAP2-6|SNRK2 Complex RAP2-6[AT1G43160],SNRK2[AT1G10940,AT1G78290,AT4G33950,SOTUB02G032470.1.1] InsP8 Metabolite Signalling - Phospho-inosytol-phosphate (PIP) Signalling - Phospho-inosytol-phosphate (PIP) soluble inositol pentakisphosphate VIH1[AT5G15070] PlantCoding VIH1 fc00430 Signalling - Phospho-inosytol-phosphate (PIP) Signalling - Phospho-inosytol-phosphate (PIP) Phosphoglycerate mutase-like family protein kegg:at5g15070 AT5G15070 CDG1[AT3G26940] PlantCoding CDG1 fc00434 Protein kinase superfamily protein AT3G26940 HSP70[AT3G12580] PlantCoding HSP70 fc00433 HSP70-4 is present in leaf, localised to cytoplasm, and heat inducible. Addiontal members of the HSP70 family are still to be added to this functional cluster. Signalling - Heat-shock proteins (HSPs),Stress - Heat heat shock protein 70 doi:10.1093/jxb/erab549,pmid:11599561,metacyc:eg10241 AT3G12580 HSP70|HSP90|SGT1 Complex HSP70,HSP90,SGT1 ENDO1[AT1G11190] PlantCoding ENDO1 fc00431 Signalling - Senescence Signalling - Senescence bifunctional nuclease i AT1G11190 CML12[AT2G41100] PlantCoding CML12 fc00435 Signalling - Calcium,Hormone - Auxins (AUX) Calcium-binding EF hand family protein AT2G41100 CML12|PID Complex CML12[AT2G41100],PID[AT2G34650] PID[AT2G34650] PlantCoding PID fc00436 Protein kinase superfamily protein AT2G34650 PBP1[AT5G54490] PlantCoding PBP1 fc00437 pinoid-binding protein 1 AT5G54490 PBP1|PID Complex PBP1[AT5G54490],PID[AT2G34650] KRP1[AT4G27280] PlantCoding KRP1 fc00438 Signalling - Calcium,Hormone - Auxins (AUX) Calcium-binding EF-hand family protein AT4G27280 CMI1|ICR1 Complex KRP1[AT4G27280],ICR1[AT1G17140] ICR1[AT1G17140] PlantCoding ICR1 fc00439 Hormone - Auxins (AUX) Hormone - Auxins (AUX) interactor of constitutive active rops 1 AT1G17140 miR398b[AT5G14545] PlantCoding miR398b fc00441 Stress - Heat Stress - Heat microRNA 398B AT5G14545 HSFA1b[AT5G16820] PlantCoding HSFA1b fc00440 Stress - Heat Stress - Heat heat shock factor 3 AT5G16820 NGA1[AT2G46870] PlantCoding NGA1 fc00442 Hormone - Abscisic acid (ABA),Stress - Drought AP2/B3-like transcriptional factor family protein AT2G46870 BGLU18[AT1G52400] PlantCoding BGLU18 fc00443 Hormone - Abscisic acid (ABA),Stress - Drought beta glucosidase 18 kegg:k14595 AT1G52400 ABA-GE Metabolite Hormone - Abscisic acid (ABA) Hormone - Abscisic acid (ABA) Abscisic acid glucose ester chebi:22151,pubchem:47205283,kegg:c15970 8′ OH-ABA Metabolite Hormone - Abscisic acid (ABA) Hormone - Abscisic acid (ABA) 8′-Hydroxyl ABA chebi:20805,pubchem:17396506,kegg:c15514 CYP707A3[AT5G45340] PlantCoding CYP707A3 fc00444 Hormone - Abscisic acid (ABA) Hormone - Abscisic acid (ABA) Cytochrome P450, family 707, subfamily A, polypeptide 3 kegg:k09843 AT5G45340 Phaseic acid Metabolite Hormone - Abscisic acid (ABA) Hormone - Abscisic acid (ABA) Phaseic acid chebi:28205,pubchem:5281527,kegg:c09707 DPA Metabolite Hormone - Abscisic acid (ABA) Hormone - Abscisic acid (ABA) Dihydrophaseic acid chebi:23757,pubchem:138319162,metacyc:cpd-7726,kegg:c15971 PAR[unknown] PlantAbstract PAR fc00445 Hormone - Abscisic acid (ABA) Hormone - Abscisic acid (ABA) Phaseic acid reductase oxIAA Metabolite Hormone - Auxins (AUX) Hormone - Auxins (AUX) 2-oxindole-3-acetic acid chebi:133221,pubchem:3080590,metacyc:2-oxindole-3-acetic-acid,kegg:c22202 DAO1[AT1G14130] PlantCoding DAO1 fc00446 Hormone - Auxins (AUX) Hormone - Auxins (AUX) 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein AT1G14130 UGT79B2[AT4G27560] PlantCoding UGT79B2 fc00448 Secondary metabolism - Anthocyanins Secondary metabolism - Anthocyanins UDP-Glycosyltransferase superfamily protein AT4G27560 DREB1B[AT4G25490] PlantCoding DREB1B fc00449 Secondary metabolism - Anthocyanins Secondary metabolism - Anthocyanins C-repeat/DRE binding factor 1 AT4G25490 UGT79B3[AT4G27570] PlantCoding UGT79B3 fc00450 Secondary metabolism - Anthocyanins Secondary metabolism - Anthocyanins UDP-Glycosyltransferase superfamily protein AT4G27570 12-OH-JA Metabolite Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) 12-hydroxyjasmonate chebi:133220,pubchem:44123344,metacyc:cpd-11260,kegg:c21385 FMO1[AT1G19250] PlantCoding FMO1 fc00454 flavin-dependent monooxygenase 1 AT1G19250 ROP9|SlRBOHB Complex ROP9[SOLYC03G114070.3.1],RBOHB [SOLYC03G117980.3.1] RBOHB [SOLYC03G117980.3.1] PlantCoding RBOHB fc00453 whitefly-induced gp91-phox SOLYC03G117980.3.1 ROP9[SOLYC03G114070.3.1] PlantCoding ROP9 fc00452 Rac-like small GTP-binding protein SOLYC03G114070.3.1 ALD1[AT2G13810] PlantCoding ALD1 fc00455 Hormone - Pipecolic acid Hormone - Pipecolic acid AGD2-like defense response protein 1 AT2G13810 FKBP42|HSP90 Complex FKBP42[AT3G21640],HSP90[AT2G04030,AT3G07770,AT4G24190,AT5G52640,AT5G56000,AT5G56010,AT5G56030] FKBP42[AT3G21640] PlantCoding FKBP42 fc00457 FKBP-type peptidyl-prolyl cis-trans isomerase family protein AT3G21640 ADR1[AT1G33560] PlantCoding ADR1 fc00458 ACTIVATED DISEASE RESISTANCE 1 AT1G33560 ADR1-L1[AT4G33300] PlantCoding ADR1-L1 fc00459 ADR1-like 1 AT4G33300 ADR1-L2[AT5G04720] PlantCoding ADR1-L2 fc00460 ADR1-like 2 AT5G04720 FKBP42|CAM Complex FKBP42[AT3G21640],CAM1[AT5G37780] CAM1[AT5G37780] PlantCoding CAM1 fc00461 calmodulin 1 AT5G37780 MPK7[SOTUB08G028940.1.1] PlantCoding MPK7 fc00456 Mitogen-activated protein kinase SOTUB08G028940.1.1 ELF3[AT2G25930] PlantCoding ELF3 fc00462 Signalling - Circadian rhythm,Stress - Heat hydroxyproline-rich glycoprotein family protein AT2G25930 PHOR1[SOTUB04G023130.1.1] PlantCoding PHOR1 fc00447 Hormone - Gibberellin (GA) Hormone - Gibberellin (GA) U-box domain-containing protein SOTUB04G023130.1.1 CBL1|CIPK1 Complex CBL1[AT4G17615],CIPK1[AT3G17510] CIPK1[AT3G17510] PlantCoding CIPK1 fc00465 CBL-interacting protein kinase 1 AT3G17510 CBL1[AT4G17615] PlantCoding CBL1 fc00464 calcineurin B-like protein 1 AT4G17615 CBL9|CIPK1 Complex CBL9[AT5G47100],CIPK1[AT3G17510] CBL9[AT5G47100] PlantCoding CBL9 fc00466 calcineurin B-like protein 9 AT5G47100 SERK4[AT2G13790] PlantCoding SERK4 fc00467 somatic embryogenesis receptor-like kinase 4 AT2G13790 GB1[AT4G34460] PlantCoding GB1 fc00468 GTP binding protein beta 1 AT4G34460 PUB13[AT3G46510] PlantCoding PUB13 fc00469 Degradation - Ubiquitination Degradation - Ubiquitination plant U-box 13 AT3G46510 WRKY40[AT1G80840] PlantCoding WRKY40 fc00470 Regulation - Transcription & Translation Regulation - Transcription & Translation WRKY DNA-binding protein 40 AT1G80840 WRKY60[AT2G25000] PlantCoding WRKY60 fc00471 Regulation - Transcription & Translation Regulation - Transcription & Translation WRKY DNA-binding protein 60 AT2G25000 NUDT6[AT2G04450] PlantCoding NUDT6 fc00472 nudix hydrolase homolog 6 AT2G04450 NUDT7[AT4G12720] PlantCoding NUDT7 fc00473 ARABIDOPSIS THALIANA NUDIX HYDROLASE HOMOLOG 7 AT4G12720 MLO2[AT1G11310] PlantCoding MLO2 fc00474 MILDEW RESISTANCE LOCUS O 2 AT1G11310 BON1[AT5G61900] PlantCoding BON1 fc00475 Calcium-dependent phospholipid-binding Copine family protein AT5G61900 BAP1[AT3G61190] PlantCoding BAP1 fc00476 BON association protein 1 AT3G61190 BAP2[AT2G45760] PlantCoding BAP2 fc00477 BON association protein 2 AT2G45760 PHYB[AT2G18790] PlantCoding PHYB fc00478 phytochrome B AT2G18790 FKBP62|HSP90.1 Complex FKBP62[AT3G25230],HSP90[AT2G04030,AT3G07770,AT4G24190,AT5G52640,AT5G56000,AT5G56010,AT5G56030] FKBP62[AT3G25230] PlantCoding FKBP62 fc00479 Stress - Heat Stress - Heat rotamase FKBP 1 pubchem:822117,kegg:k09571 AT3G25230 CBL1|CIPK23 Complex CBL1[AT4G17615],CIPK23[AT1G30270] CIPK23[AT1G30270] PlantCoding CIPK23 fc00480 Signalling - Calcium,Stress - Drought CBL-interacting protein kinase 23 AT1G30270 CBL9|CIPK23 Complex CBL9[AT5G47100],CIPK23[AT1G30270] ABF1|IDD14 Complex IDD14[AT1G68130],AREB/ABF[AT1G45249,AT1G49720,AT3G19290,AT4G34000] IDD14[AT1G68130] PlantCoding IDD14 fc00481 indeterminate(ID)-domain 14 AT1G68130 ABF2|IDD14 Complex IDD14[AT1G68130],AREB/ABF[AT1G45249,AT1G49720,AT3G19290,AT4G34000] ABF3|IDD14 Complex IDD14[AT1G68130],AREB/ABF[AT1G45249,AT1G49720,AT3G19290,AT4G34000] ABF4|IDD14 Complex IDD14[AT1G68130],AREB/ABF[AT1G45249,AT1G49720,AT3G19290,AT4G34000] HSFA1d|PIF4 Complex HSFA1d[AT1G32330],PIF4[AT2G43010] HSFA1d[AT1G32330] PlantCoding HSFA1d fc00482 heat shock transcription factor A1d AT1G32330 PHYA[AT1G09570] PlantCoding PHYA fc00483 phytochrome A AT1G09570 red light ForeignAbiotic red light ABI4|RGL2 Complex DELLA[AT1G14920,AT1G66350,AT2G01570,AT3G03450,AT5G17490],ABI4[AT2G40220] ABI4[AT2G40220] PlantCoding ABI4 fc00484 Integrase-type DNA-binding superfamily protein AT2G40220 ABI5[AT2G36270] PlantCoding ABI5 fc00485 Basic-leucine zipper (bZIP) transcription factor family protein AT2G36270 ABI5|HY5 Complex HY5[AT5G11260],ABI5[AT2G36270] CBL2|Ca2+ Complex CBL2[AT5G55990],Ca2+ CBL2[AT5G55990] PlantCoding CBL2 fc00486 Signalling - Calcium Signalling - Calcium calcineurin B-like protein 2 AT5G55990 CBL3|Ca2+ Complex CBL3[AT4G26570],Ca2+ CBL3[AT4G26570] PlantCoding CBL3 fc00487 Signalling - Calcium Signalling - Calcium calcineurin B-like 3 AT4G26570 DREB1D[AT5G51990] PlantCoding DREB1D fc00488 C-repeat-binding factor 4 AT5G51990 SRK2D[AT3G50500] PlantCoding SRK2D fc00489 SNF1-related protein kinase 2.2 AT3G50500 SPCH[AT5G53210] PlantCoding SPCH fc00490 Signalling - Growth Signalling - Growth basic helix-loop-helix (bHLH) DNA-binding superfamily protein AT5G53210 SRK2I[AT5G66880] PlantCoding SRK2I fc00491 sucrose nonfermenting 1(SNF1)-related protein kinase 2.3 AT5G66880 NPF3.1[PGSC0003DMG400025395] PlantCoding NPF3.1 fc00492 Regulation - Transcription & Translation Regulation - Transcription & Translation Nitrate transporter PGSC0003DMG400025395 NR[NITRATE REDUCTASE] PlantCoding NR fc00494 Regulation - Transcription & Translation Regulation - Transcription & Translation nitrate reductase NITRATE REDUCTASE CAX1[AT2G38170] PlantCoding CAX1 fc00493 Signalling - Calcium Signalling - Calcium cation exchanger 1 AT2G38170 CAX3[AT3G51860] PlantCoding CAX3 fc00495 Signalling - Calcium Signalling - Calcium cation exchanger 3 AT3G51860 ORE1SO2[SOLTU.DM.02G031550] PlantCoding ORE1SO2 fc00496 Regulation - Transcription & Translation Regulation - Transcription & Translation ORESARA1 SOLTU.DM.02G031550 CBL2|CIPK3|Ca2+ Complex CBL2|Ca2+,CIPK3[AT2G26980] CIPK3[AT2G26980] PlantCoding CIPK3 fc00498 CBL-interacting protein kinase 3 AT2G26980 CBL2|CIPK9|Ca2+ Complex CBL2|Ca2+,CIPK9[AT1G01140] CIPK9[AT1G01140] PlantCoding CIPK9 fc00499 CBL-interacting protein kinase 9 AT1G01140 CBL2|CIPK26|Ca2+ Complex CBL2|Ca2+,CIPK26[AT5G21326] CIPK26[AT5G21326] PlantCoding CIPK26 fc00500 Ca2+regulated serine-threonine protein kinase family protein AT5G21326 CBL3|CIPK3|Ca2+ Complex CBL3|Ca2+,CIPK3[AT2G26980] CBL3|CIPK9|Ca2+ Complex CBL3|Ca2+,CIPK9[AT1G01140] CBL3|CIPK26|Ca2+ Complex CBL3|Ca2+,CIPK26[AT5G21326] PR1|cholesterol Complex PR1[AT2G14580,AT2G14610,SOTUB09G006090.1.1,SOTUB09G006100.1.1,SOTUB09G006110.1.1],cholesterol cholesterol Metabolite Phytophthora ForeignEntity oomycete CBL2|CIPK3 Complex CBL2[AT5G55990],CIPK3[AT2G26980] CBL2|CIPK9 Complex CBL2[AT5G55990],CIPK9[AT1G01140] CBL2|CIPK23 Complex CBL2[AT5G55990],CIPK23[AT1G30270] CBL2|CIPK26 Complex CBL2[AT5G55990],CIPK26[AT5G21326] CBL3|CIPK3 Complex CBL3[AT4G26570],CIPK3[AT2G26980] CBL3|CIPK9 Complex CBL3[AT4G26570],CIPK9[AT1G01140] CBL3|CIPK23 Complex CBL3[AT4G26570],CIPK23[AT1G30270] CBL3|CIPK26 Complex CBL3[AT4G26570],CIPK26[AT5G21326] TIC56 ForeignCoding Signalling - Tuberisation Signalling - Tuberisation GYF_2 domain-containing protein n=1 other bHLH93[SOLTU.DM.02G007350] PlantCoding bHLH93 fc00501 Signalling - Tuberisation Signalling - Tuberisation Putative transcription factor bHLH93-like n=1 SOLTU.DM.02G007350 DXR[AT5G62790] PlantCoding DXR fc00502 1-deoxy-D-xylulose 5-phosphate reductoisomerase AT5G62790 PIF1[AT2G20180] PlantCoding PIF1 fc00503 phytochrome interacting factor 3-like 5 AT2G20180 PIF3-TOC1-SP6A complex Complex PIF3,4[SOTUB01G039200.1.1],SP6A[SOLTU.DM.05G026370.1] SP6A[SOLTU.DM.05G026370.1] PlantCoding SP6A fc00505 Signalling - Tuberisation Signalling - Tuberisation PEBP SOLTU.DM.05G026370.1 PIF3,4[SOTUB01G039200.1.1] PlantCoding PIF3,4 fc00504 Signalling - Tuberisation Signalling - Tuberisation BHLH transcription factor SOTUB01G039200.1.1 CLAMT[AT4G36470] PlantCoding CLAMT fc00508 Hormone - Strigolactones (SL) Hormone - Strigolactones (SL) S-adenosyl-L-methionine-dependent methyltransferases superfamily protein AT4G36470 BN2[SOTUB04G034100.1.1] PlantCoding BN2 fc00279 Bifunctional nuclease-2 Regulation - Silencing Regulation - Silencing SEC14-like protein; Bifunctional nuclease-2 gmm:20.2.4 SOTUB04G034100.1.1 MKK2[AT4G29810] PlantCoding MKK2 fc00510 MAP kinase kinase 2 AT4G29810 Photosynthesis Process Primary metabolism - Photosynthesis Primary metabolism - Photosynthesis Photosynthesis is a process in which energy from sunlight is harvested and used to fix CO2 into carbohydrates. During photosynthesis the solar energy is trapped by light-harvesting complexes, and used to split a donor molecule, generating high potential electrons that are channeled to NADP+, forming NADPH, which can be used to reduce CO2. metacyc:photoall-pwy,kegg:ath00195 CBL4|Ca2+ Complex CBL4[AT5G24270],Ca2+ CBL4[AT5G24270] PlantCoding CBL4 fc00511 Signalling - Calcium Signalling - Calcium Calcium-binding EF-hand family protein AT5G24270 CBL4|CIPK24 Complex CBL4[AT5G24270],CIPK24[AT5G35410] CIPK24[AT5G35410] PlantCoding CIPK24 fc00512 Protein kinase superfamily protein AT5G35410 CPK27[AT4G04700] PlantCoding CPK27 fc00513 calcium-dependent protein kinase 27 AT4G04700 CPK3[AT4G23650] PlantCoding CPK3 fc00514 calcium-dependent protein kinase 6 AT4G23650 PHYB-PIF3 Complex PIF3,4[AT1G09530,SOTUB07G016670.1.1] SnRK2.10[AT1G60940] PlantCoding SnRK2.10 fc00516 SNF1-related protein kinase 2.10 AT1G60940 HOP3[AT4G12400] PlantCoding HOP3 fc00517 Hormone - Jasmonate (JA) Hormone - Jasmonate (JA) stress-inducible protein gmm:20.2.1 AT4G12400 NRG1.1[AT5G66900.1] PlantCoding NRG1.1 fc00451 N REQUIREMENT GENE 1.1 AT5G66900.1 WRKY50[AT5G26170,SOTUB04G021760.1.1] PlantCoding WRKY50 fc00228 Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) WRKY family transcription factor 50 AT5G26170 SOTUB04G021760.1.1 WRKY50|TGA2 Complex WRKY50[AT5G26170,SOTUB04G021760.1.1] bZIP61[SOTUB07G024520.1.1] PlantCoding bZIP61 fc00518 BZIP transcription factor family protein gmm:27.3.35 SOTUB07G024520.1.1 NPR3L[SOTUB02G015550.1.1] PlantCoding NPR3L fc00519 NPR3L (called StNPR3/4), has been found to interact with TGAs (Tomaž, 2023). NPR1-2 protein (Fragment) gmm:27.3.61,doi:10.1093/plphys/kiac579 SOTUB02G015550.1.1 ICS1[SOTUB06G027020.1.1] PlantCoding ICS1 fc00520 Isochorismate synthase gmm:18.5.2.1 SOTUB06G027020.1.1 MIZ1[AT2G41660] PlantCoding MIZ1 fc00521 MIZU-KUSSEI-like protein (Protein of unknown function%2C DUF617) gmm:35.2 AT2G41660 CPK12|GRF8 Complex GRF8[AT5G65430],CPK12[AT5G23580] CPK12[AT5G23580] PlantCoding CPK12 fc00523 calmodulin-like domain protein kinase 9 gmm:30.3 AT5G23580 GRF8[AT5G65430] PlantCoding GRF8 fc00522 general regulatory factor 8 gmm:30.7 AT5G65430 TPK1[AT5G55630] PlantCoding TPK1 fc00524 Outward rectifying potassium channel protein gmm:34.15 AT5G55630 CIPK6|AKT1 Complex AKT1[AT2G26650],CIPK6[AT4G30960] CIPK6[AT4G30960] PlantCoding CIPK6 fc00526 SOS3-interacting protein 3 gmm:29.4 AT4G30960 AKT1[AT2G26650] PlantCoding AKT1 fc00525 K+ transporter 1 gmm:34.15 AT2G26650 CIPK16|AKT1 Complex AKT1[AT2G26650],CIPK16[AT2G25090] CIPK16[AT2G25090] PlantCoding CIPK16 fc00527 CBL-interacting protein kinase 16 gmm:29.4 AT2G25090 CIPK23|AKT1 Complex CIPK23[AT1G30270],AKT1[AT2G26650] CIPK6|CBL1 Complex CIPK6[AT4G30960],CBL1[AT4G17615] CIPK6|CBL2 Complex CIPK6[AT4G30960],CBL2[AT5G55990] CIPK6|CBL3 Complex CIPK6[AT4G30960],CBL3[AT4G26570] CIPK6|CBL9 Complex CIPK6[AT4G30960],CBL9[AT5G47100] CIPK16|CBL1 Complex CIPK16[AT2G25090],CBL1[AT4G17615] CIPK16|CBL2 Complex CIPK16[AT2G25090],CBL2[AT5G55990] CIPK16|CBL3 Complex CIPK16[AT2G25090],CBL3[AT4G26570] CIPK16|CBL9 Complex CIPK16[AT2G25090],CBL9[AT5G47100] AKT1|AIP1 Complex AKT1[AT2G26650],AIP1[AT1G07430] AIP1[AT1G07430] PlantCoding AIP1 fc00528 highly ABA-induced PP2C protein 2 gmm:17.1.2 AT1G07430 CIPK23|AIP1 Complex CIPK23[AT1G30270],AIP1[AT1G07430] CIPK8|CBL1 Complex CIPK8[AT4G24400],CBL1[AT4G17615] CIPK8[AT4G24400] PlantCoding CIPK8 fc00529 CBL-interacting protein kinase 8 gmm:29.4.1 AT4G24400 CIPK8|CBL5 Complex CIPK8[AT4G24400],CBL5[AT4G01420] CBL5[AT4G01420] PlantCoding CBL5 fc00530 calcineurin B-like protein 5 gmm:30.3 AT4G01420 CIPK8|CBL10 Complex CIPK8[AT4G24400],CBL10[AT4G33000] CBL10[AT4G33000] PlantCoding CBL10 fc00531 calcineurin B-like protein 10 gmm:30.3 AT4G33000 SOS1[AT2G01980] PlantCoding SOS1 fc00532 sodium proton exchanger (NHX7) (SOS1) gmm:34.14 AT2G01980 CIPK24|CBL10 Complex CIPK24[AT5G35410],CBL10[AT4G33000] CBL10|Ca2+ Complex CBL10[AT4G33000],Ca2+ NPR1-EDS1 Complex EDS1[AT3G48090],NPR1[AT1G64280] WRKY70|Ub Complex WRKY70[AT3G56400] NPR1|CUL3 Complex Degradation - Ubiquitination Degradation - Ubiquitination doi:10.1016/j.cell.2020.07.016 NPR1,CUL3 NPR1|CUL3A Complex NPR1[AT1G64280],CUL3A[AT1G26830] CUL3A[AT1G26830] PlantCoding CUL3A fc00533 Degradation - Ubiquitination Degradation - Ubiquitination cullin 3 kegg:k03869,gmm:29.5.11.4.5.1 AT1G26830 EDS1-WRKY18 Complex EDS1[AT3G48090] NRG1.1-EDS1 Complex NRG1.1[AT5G66900.1],EDS1[AT3G48090] TNL-effector ForeignCoding Stress - Biotic Stress - Biotic doi:10.1038/s41467-021-23614-x other Benzyl alcohol Metabolite Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) Benzyl alcohol kegg:c00556,doi:10.1093/plcell/koaf241 ADH[unknown] PlantAbstract ADH fc00534 Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) Alcohol dehydrogenase kegg:k00055,doi:10.1093/plcell/koaf241 BB Metabolite Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) Benzyl benzoate kegg:c12537,doi:10.1038/s41586-025-09175-9 BEBT[SOLYC07G049660] PlantCoding BEBT fc00535 Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) benzoyl-CoA: benzyl alcohol O-benzoyltransferase doi:10.1038/s41586-025-09280-9 SOLYC07G049660 BS Metabolite Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) Benzyl Salicylate pubchem:8363 BBH[AT5G07990] PlantCoding BBH fc00536 Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) Cytochrome P450 enzyme benzylbenzoate hydroxylase doi:10.1038/s41586-025-09280-9 AT5G07990 BSE[AT5G16080] PlantCoding BSE fc00537 Hormone - Salicylic acid (SA) Hormone - Salicylic acid (SA) Benzylsalicylate esterase doi:10.1038/s41586-025-09280-9 AT5G16080 BAG3[AT5G07220] PlantCoding BAG3 fc00538 BCL-2-associated athanogene 3 gmm:29.6.2 AT5G07220 AtMC4[AT1G79340] PlantCoding AtMC4 fc00539 metacaspase 4 gmm:29.5 AT1G79340 EDR1[AT1G08720] PlantCoding EDR1 fc00540 Signalling - MAP kinases (MAPKs),Hormone - Jasmonate (JA),Stress - Biotic Protein kinase superfamily protein gmm:29.4,doi:10.1093/plcell/koaf285 AT1G08720 PP2AB1[AT1G51690] PlantCoding PP2AB1 fc00541 Signalling - MAP kinases (MAPKs),Signalling - Perception and resistance genes,Hormone - Jasmonate (JA),Stress - Biotic protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform gmm:29.4,doi:10.1093/plcell/koaf285 AT1G51690 MPK15[AT1G73670] PlantCoding MPK15 fc00542 Signalling - MAP kinases (MAPKs),Hormone - Jasmonate (JA),Stress - Biotic MAP kinase 15 gmm:29.4,doi:10.1093/plcell/koaf285 AT1G73670